MeSH Browser

MeSH Heading: Pseudohypoaldosteronism
Tree Number(s): C12.050.351.968.419.815.770; C12.200.777.419.815.770; C12.950.419.815.770; C16.320.831.770
Unique ID: D011546
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011546
Scope Note: A heterogeneous group of disorders characterized by renal electrolyte transport dysfunctions. Congenital forms are rare autosomal disorders characterized by neonatal hypertension, HYPERKALEMIA, increased RENIN activity and ALDOSTERONE concentration. The Type I features HYPERKALEMIA with sodium wasting; Type II, HYPERKALEMIA without sodium wasting. Pseudohypoaldosteronism can be the result of a defective renal electrolyte transport protein or acquired after KIDNEY TRANSPLANTATION.
Entry Term(s): Familial Hyperpotassemia and Hypertension; Familial Hypertensive Hyperkalemia; Gordon Hyperkalemia-Hypertension Syndrome; Hyperpotassemia and Hypertension, Familial; Hypertensive Hyperkalemia, Familial; Pseudohypoaldosteronism Type 1; Pseudohypoaldosteronism Type 1, Autosomal Dominant; Pseudohypoaldosteronism Type 1, Autosomal Recessive; Pseudohypoaldosteronism Type 2; Pseudohypoaldosteronism Type I; Pseudohypoaldosteronism Type II; Pseudohypoaldosteronism, Type I; Pseudohypoaldosteronism, Type I, Autosomal Dominant; Pseudohypoaldosteronism, Type I, Autosomal Recessive; Pseudohypoaldosteronism, Type II
Previous Indexing: Aldosterone (1971-1987); Hyperaldosteronism (1975-1980); Renal Tubular Transport, Inborn Errors (1971-1987)
See Also: Epithelial Sodium Channels; Receptors, Mineralocorticoid
Public MeSH Note: 1991; see RENAL TUBULAR TRANSPORT, INBORN ERRORS 1988-90
History Note: 1991(1988); use RENAL TUBULAR TRANSPORT, INBORN ERRORS 1988-90
Date Established: 1991/01/01
Date of Entry: 1987/03/13
Revision Date: 2021/06/30

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Urogenital Diseases [C12]
- Female Urogenital Diseases and Pregnancy Complications [C12.050]
  - Female Urogenital Diseases [C12.050.351]
    - Urologic Diseases [C12.050.351.968]
      - Kidney Diseases [C12.050.351.968.419]
        
        Renal Tubular Transport, Inborn Errors [C12.050.351.968.419.815]
        
        Acidosis, Renal Tubular [C12.050.351.968.419.815.093]
        
        Bartter Syndrome [C12.050.351.968.419.815.279]
        
        Dent Disease [C12.050.351.968.419.815.364]
        
        Fanconi Syndrome [C12.050.351.968.419.815.450]
        
        Gitelman Syndrome [C12.050.351.968.419.815.491]
        
        Glycosuria, Renal [C12.050.351.968.419.815.532]
        
        Hypophosphatemia, Familial [C12.050.351.968.419.815.647]
        
        Liddle Syndrome [C12.050.351.968.419.815.683]
        
        Oculocerebrorenal Syndrome [C12.050.351.968.419.815.720]
        
        Pseudohypoaldosteronism [C12.050.351.968.419.815.770]
        
        Renal Aminoacidurias [C12.050.351.968.419.815.885]

Urogenital Diseases [C12]
- Male Urogenital Diseases [C12.200]
  - Urologic Diseases [C12.200.777]
    - Kidney Diseases [C12.200.777.419]
      - Renal Tubular Transport, Inborn Errors [C12.200.777.419.815]
        
        Acidosis, Renal Tubular [C12.200.777.419.815.093]
        
        Bartter Syndrome [C12.200.777.419.815.279]
        
        Dent Disease [C12.200.777.419.815.364]
        
        Fanconi Syndrome [C12.200.777.419.815.450]
        
        Gitelman Syndrome [C12.200.777.419.815.491]
        
        Glycosuria, Renal [C12.200.777.419.815.532]
        
        Hypophosphatemia, Familial [C12.200.777.419.815.647]
        
        Liddle Syndrome [C12.200.777.419.815.683]
        
        Oculocerebrorenal Syndrome [C12.200.777.419.815.720]
        
        Pseudohypoaldosteronism [C12.200.777.419.815.770]
        
        Renal Aminoacidurias [C12.200.777.419.815.885]

Urogenital Diseases [C12]
- Urologic Diseases [C12.950]
  - Kidney Diseases [C12.950.419]
    - Renal Tubular Transport, Inborn Errors [C12.950.419.815]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
  - Renal Tubular Transport, Inborn Errors [C16.320.831]

Pseudohypoaldosteronism Preferred

Pseudohypoaldosteronism, Type I, Autosomal Dominant Narrower

Pseudohypoaldosteronism, Type I, Autosomal Recessive Narrower

Pseudohypoaldosteronism, Type II Narrower

Concept UI: M0461207
Scope Note: Autosomal dominant syndrome of renal electrolyte transport dysfunctions. The clinical features include salt-sensitive hypertension, renal HYPERKALEMIA without sodium wasting, normal glomerular filtration rate and metabolic acidosis (hyperchloremic acidemia and HYPERCALCIURIA). Wnk1 and Wnk4 mutations are responsible for the disorder.
Terms: Pseudohypoaldosteronism, Type II Preferred Term
Term UI T573804
Date02/23/2004
LexicalTag NON
ThesaurusID; Pseudohypoaldosteronism Type II
Term UI T000903210
Date06/23/2016
LexicalTag NON
ThesaurusID GHR (2014); Gordon Hyperkalemia-Hypertension Syndrome
Term UI T735252
Date02/18/2009
LexicalTag EPO
ThesaurusID; Pseudohypoaldosteronism Type 2
Term UI T735358
Date02/20/2009
LexicalTag NON
ThesaurusID

Pseudohypoaldosteronism, Type I Narrower

Concept UI: M0529642
Scope Note: Rare autosomal disorder of renal electrolyte transport dysfunctions. The Type I features HYPERKALEMIA with sodium wasting; Type II, HYPERKALEMIA without sodium wasting. Loss of function mutations in EPITHELIAL SODIUM CHANNELS subunits (autosomal dominant) or MINERALOCORTICOID RECEPTORS (autosomal recessive) cause the disorder. Different mutations in EPITHELIAL SODIUM CHANNELS subunits cause Liddle syndrome.
Terms: Pseudohypoaldosteronism, Type I Preferred Term
Term UI T735351
Date02/20/2009
LexicalTag NON
ThesaurusID NLM (2010); Pseudohypoaldosteronism Type 1
Term UI T735355
Date02/20/2009
LexicalTag NON
ThesaurusID; Pseudohypoaldosteronism Type I
Term UI T842353
Date04/18/2013
LexicalTag NON
ThesaurusID GHR (2014)

Hyperpotassemia and Hypertension, Familial Narrower

Pseudohypoaldosteronism MeSH Descriptor Data 2024