MeSH Browser

MeSH Heading: Nuclear Receptor Subfamily 1, Group F, Member 1
Tree Number(s): D12.776.260.643.100; D12.776.476.156.437; D12.776.826.209.100
Unique ID: D057094
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D057094
Scope Note: A DNA-binding orphan nuclear receptor that positively regulates expression of ARNTL TRANSCRIPTION FACTORS and is a regulatory component of the circadian clock system. The protein also has a role in neuron cell survival and differentiation in that loss of function mutations of its gene result in the mouse phenotype referred to as the STAGGERER MOUSE.
Entry Term(s): Nuclear Receptor NR1F1; Nuclear Receptor ROR-alpha; Nuclear Receptor RZR-alpha; RAR-Related Orphan Receptor A; Retinoid-Related Orphan Receptor-alpha; Retinoid-Related Orphan Receptor-alpha1; Retinoid-Related Orphan Receptor-alpha2; Retinoid-Related Orphan Receptor-alpha3; Retinoid-Related Orphan Receptor-alpha4
Registry Numbers: 0
Public MeSH Note: 2010; RAR-RELATED ORPHAN RECEPTOR A (now NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 1) was indexed under TRANS-ACTIVATORS and RECEPTORS, CYTOPLASMIC AND NUCLEAR 1996-2009
History Note: 2010(1996)
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2018/07/02

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0534525
Registry Numbers: 0
Scope Note: A DNA-binding orphan nuclear receptor that positively regulates expression of ARNTL TRANSCRIPTION FACTORS and is a regulatory component of the circadian clock system. The protein also has a role in neuron cell survival and differentiation in that loss of function mutations of its gene result in the mouse phenotype referred to as the STAGGERER MOUSE.
Terms: Nuclear Receptor Subfamily 1, Group F, Member 1 Preferred Term
Term UI T749220
Date04/13/2009
LexicalTag NON
ThesaurusID NLM (2010); Nuclear Receptor ROR-alpha
Term UI T749002
Date04/09/2009
LexicalTag ABX
ThesaurusID NLM (2010); RAR-Related Orphan Receptor A
Term UI T750465
Date05/04/2009
LexicalTag ABX
ThesaurusID NLM (2010); Retinoid-Related Orphan Receptor-alpha
Term UI T750466
Date05/04/2009
LexicalTag NON
ThesaurusID NLM (2010); Nuclear Receptor NR1F1
Term UI T750471
Date05/04/2009
LexicalTag NON
ThesaurusID NLM (2010)

Nuclear Receptor Subfamily 1, Group F, Member 1 MeSH Descriptor Data 2025