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Nuclear Receptor Subfamily 1, Group D, Member 1 MeSH Descriptor Data 2022


MeSH Heading
Nuclear Receptor Subfamily 1, Group D, Member 1
Tree Number(s)
D12.776.260.643.080
D12.776.476.156.300
D12.776.826.209.080
Unique ID
D056953
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D056953
Scope Note
A DNA-binding orphan nuclear receptor that negatively regulates expression of ARNTL TRANSCRIPTION FACTORS and plays a role as a regulatory component of the circadian clock system. The Nr1d1 nuclear receptor expression is cyclically-regulated by a feedback loop involving its positive regulation by CLOCK PROTEIN; BMAL1 PROTEIN heterodimers and its negative regulation by CRYPTOCHROME and PERIOD PROTEINS.
Entry Term(s)
Nuclear Receptor NR1D1
Rev-erb-alpha Nuclear Receptors
V-erbA-Related Protein EAR-1
Registry Number
0
Previous Indexing
DNA-Binding Proteins (1990-2009)
Receptors, Cytoplasmic and Nuclear (1990-2009)
Public MeSH Note
2010
History Note
2010
Date Established
2010/01/01
Date of Entry
2009/07/06
Revision Date
2018/07/02
Nuclear Receptor Subfamily 1, Group D, Member 1 Preferred
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