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DAX-1 Orphan Nuclear Receptor MeSH Descriptor Data 2024


MeSH Heading
DAX-1 Orphan Nuclear Receptor
Tree Number(s)
D12.776.826.209.059
D12.776.930.780.625.186
Unique ID
D057137
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D057137
Scope Note
An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike most orphan nuclear receptors in that it appears to lack an essential DNA-binding domain and instead acts as a transcriptional co-repressor. Mutations in the gene Dax-1 cause congenital adrenal hypoplasia.
Entry Term(s)
DSS-AHC Critical Region on the X Chromosome, Gene 1 Protein
NR0B1 Protein
Nuclear Receptor 0B1
Nuclear Receptor DAX-1
Nuclear Receptor NR0B1
Nuclear Receptor Subfamily 0, Group B, Member 1
Public MeSH Note
2010; DAX-1 ORPHAN NUCLEAR RECEPTOR was indexed under DNA-BINDING PROTEINS, REPRESSOR PROTEINS, and RECEPTORS, RETINOIC ACID 2003-2009, and under TRANSCRIPTION FACTORS 1994-2003
History Note
2010(1995)
Date Established
2010/01/01
Date of Entry
2009/07/06
Revision Date
2016/07/01
DAX-1 Orphan Nuclear Receptor Preferred
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