MeSH Browser

MeSH Heading: DAX-1 Orphan Nuclear Receptor
Tree Number(s): D12.776.826.209.059; D12.776.930.780.625.186
Unique ID: D057137
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D057137
Scope Note: An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike most orphan nuclear receptors in that it appears to lack an essential DNA-binding domain and instead acts as a transcriptional co-repressor. Mutations in the gene Dax-1 cause congenital adrenal hypoplasia.
Entry Term(s): DSS-AHC Critical Region on the X Chromosome, Gene 1 Protein; NR0B1 Protein; Nuclear Receptor 0B1; Nuclear Receptor DAX-1; Nuclear Receptor NR0B1; Nuclear Receptor Subfamily 0, Group B, Member 1
Public MeSH Note: 2010; DAX-1 ORPHAN NUCLEAR RECEPTOR was indexed under DNA-BINDING PROTEINS, REPRESSOR PROTEINS, and RECEPTORS, RETINOIC ACID 2003-2009, and under TRANSCRIPTION FACTORS 1994-2003
History Note: 2010(1995)
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2016/07/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0534812
Scope Note: An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike most orphan nuclear receptors in that it appears to lack an essential DNA-binding domain and instead acts as a transcriptional co-repressor. Mutations in the gene Dax-1 cause congenital adrenal hypoplasia.
Terms: DAX-1 Orphan Nuclear Receptor Preferred Term
Term UI T749548
Date04/17/2009
LexicalTag ABX
ThesaurusID NLM (2010); NR0B1 Protein
Term UI T000900757
Date05/10/2016
LexicalTag ABX
ThesaurusID NLM (2017); DSS-AHC Critical Region on the X Chromosome, Gene 1 Protein
Term UI T749547
Date04/17/2009
LexicalTag NON
ThesaurusID NLM (2010); Nuclear Receptor NR0B1
Term UI T750461
Date05/04/2009
LexicalTag ABX
ThesaurusID NLM (2010); Nuclear Receptor 0B1
Term UI T749549
Date04/17/2009
LexicalTag NON
ThesaurusID NLM (2010); Nuclear Receptor DAX-1
Term UI T749550
Date04/17/2009
LexicalTag ABX
ThesaurusID NLM (2010); Nuclear Receptor Subfamily 0, Group B, Member 1
Term UI T749551
Date04/17/2009
LexicalTag NON
ThesaurusID NLM (2010)

DAX-1 Orphan Nuclear Receptor MeSH Descriptor Data 2024