MeSH Browser

MeSH Heading: SNARE Proteins
Tree Number(s): D12.776.543.512.249; D12.776.543.990.775
Unique ID: D050600
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050600
Scope Note: A superfamily of small proteins which are involved in the MEMBRANE FUSION events, intracellular protein trafficking and secretory processes. They share a homologous SNARE motif. The SNARE proteins are divided into subfamilies: QA-SNARES; QB-SNARES; QC-SNARES; and R-SNARES. The formation of a SNARE complex (composed of one each of the four different types SNARE domains (Qa, Qb, Qc, and R)) mediates MEMBRANE FUSION. Following membrane fusion SNARE complexes are dissociated by the NSFs (N-ETHYLMALEIMIDE-SENSITIVE FACTORS), in conjunction with SOLUBLE NSF ATTACHMENT PROTEIN, i.e., SNAPs (no relation to SNAP 25.)
Entry Term(s): NSF Attachment Protein Receptor; Receptor, SNAP; SNAP Receptor; SNAP Receptors; SNARE; SNARE Protein; SNAREs; Soluble N-ethylmaleimide-Sensitive-Factor Attachment Protein Receptor; Target Membrane SNARE Proteins; Target SNARE Proteins; Vesicle SNARE Proteins; Vesicular SNARE Proteins; t-SNARE; tSNAREs; v-SNARE; v-SNAREs
Previous Indexing: Membrane Proteins (1994-2005); Vesicular Transport Proteins (2004-2005)
Public MeSH Note: 2006; SNAP RECEPTOR (now SNARE PROTEINS) was indexed under MEMBRANE PROTEINS 1995-2003 and VESICULAR TRANSPORT PROTEINS 2004-2005
History Note: 2006 (1995)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Fusion Proteins [D12.776.543.512]
      - SNARE Proteins [D12.776.543.512.249]
        
        Q-SNARE Proteins [D12.776.543.512.249.500]
        
        R-SNARE Proteins [D12.776.543.512.249.750]
      - Viral Fusion Proteins [D12.776.543.512.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Vesicular Transport Proteins [D12.776.543.990]

SNARE Proteins Preferred

Concept UI: M0250560
Scope Note: A superfamily of small proteins which are involved in the MEMBRANE FUSION events, intracellular protein trafficking and secretory processes. They share a homologous SNARE motif. The SNARE proteins are divided into subfamilies: QA-SNARES; QB-SNARES; QC-SNARES; and R-SNARES. The formation of a SNARE complex (composed of one each of the four different types SNARE domains (Qa, Qb, Qc, and R)) mediates MEMBRANE FUSION. Following membrane fusion SNARE complexes are dissociated by the NSFs (N-ETHYLMALEIMIDE-SENSITIVE FACTORS), in conjunction with SOLUBLE NSF ATTACHMENT PROTEIN, i.e., SNAPs (no relation to SNAP 25.)
Terms: SNARE Proteins Preferred Term
Term UI T620724
Date11/30/2004
LexicalTag ACX
ThesaurusID NLM (2006); NSF Attachment Protein Receptor
Term UI T280561
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); Receptor, SNAP
Term UI T280564
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2006); SNAP Receptor
Term UI T280565
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2006); SNAP Receptors
Term UI T280562
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2006); SNARE
Term UI T280563
Date01/01/1955
LexicalTag ACR
ThesaurusID NLM (2006); SNAREs
Term UI T626440
Date12/29/2004
LexicalTag ACR
ThesaurusID NLM (2006); SNARE Protein
Term UI T001010395
Date03/17/2020
LexicalTag NON
ThesaurusID NLM (2021); Soluble N-ethylmaleimide-Sensitive-Factor Attachment Protein Receptor
Term UI T608746
Date09/09/2004
LexicalTag NON
ThesaurusID NLM (2006)

Vesicle SNARE Proteins Narrower

Concept UI: M0472313
Terms: Vesicle SNARE Proteins Preferred Term
Term UI T608747
Date09/09/2004
LexicalTag ACX
ThesaurusID NLM (2006); v-SNARE
Term UI T608749
Date09/09/2004
LexicalTag ACR
ThesaurusID NLM (2006); v-SNAREs
Term UI T608748
Date09/09/2004
LexicalTag ACX
ThesaurusID NLM (2006); Vesicular SNARE Proteins
Term UI T608750
Date09/09/2004
LexicalTag ACX
ThesaurusID NLM (2006)

Target Membrane SNARE Proteins Narrower

Concept UI: M0472314
Terms: Target Membrane SNARE Proteins Preferred Term
Term UI T608751
Date09/09/2004
LexicalTag ACX
ThesaurusID NLM (2006); t-SNARE
Term UI T608752
Date09/09/2004
LexicalTag ACR
ThesaurusID NLM (2006); Target SNARE Proteins
Term UI T608753
Date09/09/2004
LexicalTag ACX
ThesaurusID NLM (2006); tSNAREs
Term UI T626441
Date12/29/2004
LexicalTag NON
ThesaurusID NLM (2006)

SNARE Proteins MeSH Descriptor Data 2024