MeSH Browser

MeSH Heading: Atorvastatin
Tree Number(s): D03.383.129.578.075; D10.251.450.200
Unique ID: D000069059
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000069059
Scope Note: A pyrrole and heptanoic acid derivative, HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITOR (statin), and ANTICHOLESTEREMIC AGENT that is used to reduce serum levels of LDL-CHOLESTEROL; APOLIPOPROTEIN B; and TRIGLYCERIDES. It is used to increase serum levels of HDL-CHOLESTEROL in the treatment of HYPERLIPIDEMIAS, and for the prevention of CARDIOVASCULAR DISEASES in patients with multiple risk factors.
Entry Term(s): (3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid; Atorvastatin Calcium; Atorvastatin Calcium Anhydrous; Atorvastatin Calcium Hydrate; Atorvastatin Calcium Trihydrate; Atorvastatin, Calcium Salt; CI 981; CI-981; Lipitor; Liptonorm
Pharm Action: Anticholesteremic Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Registry Number: A0JWA85V8F
Related Numbers: 110862-48-1; 48A5M73Z4Q; C0GEJ5QCSO
Public MeSH Note: 2019; see ATORVASTATIN CALCIUM 2016-2018; ATORVASTATIN CALCIUM was indexed under HEPTANOIC ACIDS and PYRROLES 1990-2015
History Note: 2019 (1990)
Date Established: 2016/01/01
Date of Entry: 2015/07/10
Revision Date: 2018/07/02

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Atorvastatin MeSH Descriptor Data 2024