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Ryanodine MeSH Descriptor Data 2022


MeSH Heading
Ryanodine
Tree Number(s)
D02.455.849.291.686
D03.132.740
D03.383.129.578.805
Unique ID
D012433
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D012433
Scope Note
A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM.
Registry Number
15662-33-6
CAS Type 1 Name
Ryanodol, 3-(1H-pyrrole-2-carboxylate)
Previous Indexing
Alkaloids (1970-1974)
Public MeSH Note
91; was see under ALKALOIDS 1975-90
History Note
91(75); was see under ALKALOIDS 1975-90
Date Established
1991/01/01
Date of Entry
1974/11/19
Revision Date
2016/05/31
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