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Swainsonine MeSH Descriptor Data 2022


MeSH Heading
Swainsonine
Tree Number(s)
D03.132.830
Unique ID
D017026
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D017026
Scope Note
An indolizidine alkaloid from the plant Swainsona canescens that is a potent alpha-mannosidase inhibitor. Swainsonine also exhibits antimetastatic, antiproliferative, and immunomodulatory activity.
Entry Term(s)
Swainsonine, (1R-(2 beta,8a alpha))-Isomer
Swainsonine, (2 beta,8a alpha)-Isomer
Swainsonine, (8 alpha)-Isomer
Swainsonine, (8 alpha,8a alpha)-Isomer
Swainsonine, (8a alpha)-Isomer
Pharm Action
Adjuvants, Immunologic
Antineoplastic Agents, Phytogenic
Enzyme Inhibitors
Registry Number
RSY4RK37KQ
Related Numbers
107982-28-5
111467-60-8
116497-15-5
116497-16-6
72741-87-8
96648-51-0
CAS Type 1 Name
1,2,8-Indolizinetriol, octahydro-, (1S-(1alpha,2alpha,8beta,8abeta))-
Previous Indexing
Alkaloids (1980-1991)
Public MeSH Note
92; SWAINSONINE was indexed under ALKALOIDS 1981-91
Online Note
use SWAINSONINE (NM) to search SWAINSONINE 1981-91
History Note
92; was SWAINSONINE (NM) 1981-91
Date Established
1992/01/01
Date of Entry
1991/07/12
Revision Date
2013/07/08
Swainsonine Preferred
Swainsonine, (8a alpha)-Isomer Narrower
Swainsonine, (8 alpha)-Isomer Narrower
Swainsonine, (8 alpha,8a alpha)-Isomer Narrower
Swainsonine, (1R-(2 beta,8a alpha))-Isomer Narrower
Swainsonine, (2 beta,8a alpha)-Isomer Narrower
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