NLM Logo

Camptothecin MeSH Descriptor Data 2022


MeSH Heading
Camptothecin
Tree Number(s)
D03.132.151
Unique ID
D002166
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D002166
Scope Note
An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Entry Term(s)
Camptothecine
Pharm Action
Antineoplastic Agents, Phytogenic
Topoisomerase I Inhibitors
Registry Number
XT3Z54Z28A
Related Numbers
7689-03-4
CAS Type 1 Name
1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-, (S)-
Previous Indexing
Alkaloids (1966-1972)
Antineoplastic Agents (1966-1972)
Public MeSH Note
73
History Note
73
Date Established
1973/01/01
Date of Entry
1999/01/01
Revision Date
2013/07/08
Camptothecin Preferred
page delivered in 0.141s