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Colforsin MeSH Descriptor Data 2023


MeSH Heading
Colforsin
Tree Number(s)
D02.455.849.291.300
Unique ID
D005576
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D005576
Scope Note
Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant COLEUS FORSKOHLII. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.
Entry Term(s)
Coleonol
Forskolin
N,N-Dimethyl-beta-alanine-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho(2,1-b)pyran-6-yl Ester HCl
NKH 477
NKH-477
NKH477
Pharm Action
Adjuvants, Immunologic
Bronchodilator Agents
Cardiotonic Agents
Vasodilator Agents
Registry Number
1F7A44V6OU
Related Numbers
138605-00-2
66428-89-5
CAS Type 1 Name
1H-Naphtho(2,1-b)pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-
Previous Indexing
Diterpenes (1974-1985)
Terpenes (1966-1973)
Public MeSH Note
2014; see FORSKOLIN 1986-2013
History Note
2014(1986)
Date Established
1986/01/01
Date of Entry
1985/03/08
Revision Date
2015/06/17
Colforsin Preferred
NKH 477 Narrower
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