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Retinaldehyde MeSH Descriptor Data 2023


MeSH Heading
Retinaldehyde
Tree Number(s)
D02.047.850
D02.455.326.271.665.202.495.690
D02.455.426.392.368.367.379.249.700.690
D02.455.849.131.495.690
D02.455.849.291.605
D23.767.261.700.690
Unique ID
D012172
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D012172
Annotation
/biosyn /‌physiol permitted
Scope Note
A diterpene derived from the carotenoid VITAMIN A which functions as the active component of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation straightens-out the bend of the retinal molecule and causes a change in the shape of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed reactions convert the 11-trans-retinal back to the cis-isomer.
Entry Term(s)
11-cis-Retinal
11-trans-Retinal
3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-Nonatetraenal
Axerophthal
Retinal
Retinene
Retinyl Aldehydde
Vitamin A Aldehyde
all-trans-Retinal
Registry Number
RR725D715M
Related Numbers
116-31-4
Public MeSH Note
91; was see under RETINOIDS 1984-90; was see under VITAMIN A 1968-83
Online Note
search VITAMIN A 1968-74
History Note
91(75); was see under RETINOIDS 1984-90; was see under VITAMIN A 1968-83
Date Established
1991/01/01
Date of Entry
1999/01/01
Revision Date
2021/07/07
Retinaldehyde Preferred
11-cis-Retinal Narrower
11-trans-Retinal Narrower
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