Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

Type I Secretion Systems MeSH Descriptor Data 2025


MeSH Heading
Type I Secretion Systems
Tree Number(s)
D05.500.890.500.500
Unique ID
D000069177
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000069177
Scope Note
Gram-negative bacterial secretion systems which translocate effectors in a single step across the inner and outer membranes. The one-step secretion is carried out by a channel that passes from the CYTOPLASM, through the inner membrane, PERIPLASMIC SPACE, and outer membrane, to the EXTRACELLULAR SPACE. The specificity of type I secretions systems are determined by the specificity of the three subcomponents forming the channel - an ATP transporter (ATP-BINDING CASSETTE TRANSPORTERS); a membrane fusion protein (MEMBRANE FUSION PROTEINS); and an outer membrane protein (BACTERIAL OUTER MEMBRANE PROTEINS.)
Entry Term(s)
Bacterial Secretion Systems, Type I
T1SS Secretion System
Type 1 Secretion System
Type 1 Secretion Systems
Type I Secretion System
Registry Numbers
0
Previous Indexing
Bacterial Secretion Systems (2010-2015)
Public MeSH Note
2016
History Note
2016
Date Established
2016/01/01
Date of Entry
2015/07/01
Revision Date
2015/06/25
Type I Secretion Systems Preferred
page delivered in 0.124s