MeSH Browser

MeSH Heading: Type I Secretion Systems
Tree Number(s): D05.500.890.500.500
Unique ID: D000069177
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000069177
Scope Note: Gram-negative bacterial secretion systems which translocate effectors in a single step across the inner and outer membranes. The one-step secretion is carried out by a channel that passes from the CYTOPLASM, through the inner membrane, PERIPLASMIC SPACE, and outer membrane, to the EXTRACELLULAR SPACE. The specificity of type I secretions systems are determined by the specificity of the three subcomponents forming the channel - an ATP transporter (ATP-BINDING CASSETTE TRANSPORTERS); a membrane fusion protein (MEMBRANE FUSION PROTEINS); and an outer membrane protein (BACTERIAL OUTER MEMBRANE PROTEINS.)
Entry Term(s): Bacterial Secretion Systems, Type I; T1SS Secretion System; Type 1 Secretion System; Type 1 Secretion Systems; Type I Secretion System
Previous Indexing: Bacterial Secretion Systems (2010-2015)
Public MeSH Note: 2016
History Note: 2016
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2015/06/25

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000604917
Scope Note: Gram-negative bacterial secretion systems which translocate effectors in a single step across the inner and outer membranes. The one-step secretion is carried out by a channel that passes from the CYTOPLASM, through the inner membrane, PERIPLASMIC SPACE, and outer membrane, to the EXTRACELLULAR SPACE. The specificity of type I secretions systems are determined by the specificity of the three subcomponents forming the channel - an ATP transporter (ATP-BINDING CASSETTE TRANSPORTERS); a membrane fusion protein (MEMBRANE FUSION PROTEINS); and an outer membrane protein (BACTERIAL OUTER MEMBRANE PROTEINS.)
Terms: Type I Secretion Systems Preferred Term
Term UI T000878676
Date04/22/2015
LexicalTag NON
ThesaurusID NLM (2016); Type I Secretion System
Term UI T000878678
Date04/22/2015
LexicalTag NON
ThesaurusID NLM (2016); Type 1 Secretion System
Term UI T000878679
Date04/22/2015
LexicalTag NON
ThesaurusID NLM (2016); Bacterial Secretion Systems, Type I
Term UI T000878680
Date04/22/2015
LexicalTag NON
ThesaurusID NLM (2016); Type 1 Secretion Systems
Term UI T000879776
Date05/15/2015
LexicalTag NON
ThesaurusID NLM (2016); T1SS Secretion System
Term UI T000881666
Date06/11/2015
LexicalTag NON
ThesaurusID NLM (2016)

Type I Secretion Systems MeSH Descriptor Data 2024