MeSH Browser

MeSH Heading: Type II Secretion Systems
Tree Number(s): D05.500.890.500.750
Unique ID: D000069178
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000069178
Scope Note: Gram-negative bacterial secretion systems which carry out the secretion of folded proteins.T2SSs secrete folded proteins from the PERIPLASMIC SPACE that have been exported there by SEC TRANSLOCASE or TAT SECRETION SYSTEMS, or they secrete folded proteins directly from the CYTOPLASM. The T2SSs have four substructures, an ATPase, an inner membrane platform, a pseudopilin, and secretin, an outer membrane complex which is a channel for secretion. (This bacterial secretin is not the same as the mammalian hormone also named SECRETIN.)
Entry Term(s): Bacterial Secretion System, Type II; T2SS Secretion System; Type 2 Secretion System; Type 2 Secretion Systems; Type II Secretion System
Previous Indexing: Bacterial Secretion Systems (2010-2015)
Public MeSH Note: 2016
History Note: 2016
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2015/06/25

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000604919
Scope Note: Gram-negative bacterial secretion systems which carry out the secretion of folded proteins.T2SSs secrete folded proteins from the PERIPLASMIC SPACE that have been exported there by SEC TRANSLOCASE or TAT SECRETION SYSTEMS, or they secrete folded proteins directly from the CYTOPLASM. The T2SSs have four substructures, an ATPase, an inner membrane platform, a pseudopilin, and secretin, an outer membrane complex which is a channel for secretion. (This bacterial secretin is not the same as the mammalian hormone also named SECRETIN.)
Terms: Type II Secretion Systems Preferred Term
Term UI T000878682
Date04/22/2015
LexicalTag NON
ThesaurusID NLM (2016); Type 2 Secretion System
Term UI T000879779
Date05/15/2015
LexicalTag NON
ThesaurusID NLM (2016); Type II Secretion System
Term UI T000879777
Date05/15/2015
LexicalTag NON
ThesaurusID NLM (2016); Type 2 Secretion Systems
Term UI T000879778
Date05/15/2015
LexicalTag NON
ThesaurusID NLM (2016); Bacterial Secretion System, Type II
Term UI T000879780
Date05/15/2015
LexicalTag NON
ThesaurusID NLM (2016); T2SS Secretion System
Term UI T000881669
Date06/11/2015
LexicalTag NON
ThesaurusID NLM (2016)

Type II Secretion Systems MeSH Descriptor Data 2024