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Type VII Secretion Systems MeSH Descriptor Data 2024

MeSH Heading
Type VII Secretion Systems
Tree Number(s)
Unique ID
RDF Unique Identifier
Scope Note
Bacterial secretion systems found in bacteria that have a MYCOLIC ACID-containing outer membrane such as MYCOBACTERIACEAE; Corynebacteriaceae; and NOCARDIACEAE. These are also known as ESX secretion systems because the first to be discovered is involved in secreting major virulence factors EsxA and EsxB. There are several subtypes of T7SSs including ESX-1, ESX-2, ESX-3, ESX-4, and ESX-5 secretion systems. The subtypes share some core components including an inner membrane channel-forming ATPase complex, a membrane-anchored mycosin, and a second channel that spans the outer mycolic acid-containing membrane.
Entry Term(s)
ESX Secretion System
ESX Secretion Systems
Secretion Systems, ESX
Secretion Systems, Type 7
Secretion Systems, Type VII
T7SS Secretion System
Type 7 Secretion System
Type 7 Secretion Systems
Type VII Secretion System
Registry Number
Previous Indexing
Bacterial Secretion Systems (2010-2015)
Public MeSH Note
History Note
Date Established
Date of Entry
Revision Date
Type VII Secretion Systems Preferred
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