MeSH Browser

MeSH Heading: Dystonin
Tree Number(s): D12.776.220.790.625
Unique ID: D000071821
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071821
Scope Note: A plakin characterized by repeat sequences homologous to SPECTRIN and PLECTIN and C-terminal EF HAND MOTIFS. It functions as an integrator of INTERMEDIATE FILAMENTS, ACTIN and MICROTUBULES in cytoskeleton networks. It is required for anchoring intermediate filaments to the actin cytoskeleton in neural and muscle cells as well as anchoring KERATIN-containing intermediate filaments to HEMIDESMOSOMES in EPITHELIAL CELLS.
Entry Term(s): 230 kDa Bullous Pemphigoid Antigen; 230-240 kDa Bullous Pemphigoid Antigen; Bullous Pemphigoid Antigen 1; Hemidesmosomal Plaque Protein
Previous Indexing: Carrier Proteins (1995-2016); Cytoskeletal Proteins (1995-2016); Nerve Tissue Proteins (1995-2016)
Public MeSH Note: 2017
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/04/15

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000615558
Scope Note: A plakin characterized by repeat sequences homologous to SPECTRIN and PLECTIN and C-terminal EF HAND MOTIFS. It functions as an integrator of INTERMEDIATE FILAMENTS, ACTIN and MICROTUBULES in cytoskeleton networks. It is required for anchoring intermediate filaments to the actin cytoskeleton in neural and muscle cells as well as anchoring KERATIN-containing intermediate filaments to HEMIDESMOSOMES in EPITHELIAL CELLS.
Terms: Dystonin Preferred Term
Term UI T000896784
Date03/08/2016
LexicalTag NON
ThesaurusID NLM (2017); Hemidesmosomal Plaque Protein
Term UI T000896786
Date03/08/2016
LexicalTag NON
ThesaurusID NLM (2017); 230 kDa Bullous Pemphigoid Antigen
Term UI T000896787
Date03/08/2016
LexicalTag NON
ThesaurusID NLM (2017); 230-240 kDa Bullous Pemphigoid Antigen
Term UI T000896788
Date03/08/2016
LexicalTag NON
ThesaurusID NLM (2017); Bullous Pemphigoid Antigen 1
Term UI T000896789
Date03/08/2016
LexicalTag NON
ThesaurusID NLM (2017)

Dystonin MeSH Descriptor Data 2024