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Dystonin MeSH Descriptor Data 2022


MeSH Heading
Dystonin
Tree Number(s)
D12.776.220.790.625
Unique ID
D000071821
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071821
Scope Note
A plakin characterized by repeat sequences homologous to SPECTRIN and PLECTIN and C-terminal EF HAND MOTIFS. It functions as an integrator of INTERMEDIATE FILAMENTS, ACTIN and MICROTUBULES in cytoskeleton networks. It is required for anchoring intermediate filaments to the actin cytoskeleton in neural and muscle cells as well as anchoring KERATIN-containing intermediate filaments to HEMIDESMOSOMES in EPITHELIAL CELLS.
Entry Term(s)
230 kDa Bullous Pemphigoid Antigen
230-240 kDa Bullous Pemphigoid Antigen
Bullous Pemphigoid Antigen 1
Hemidesmosomal Plaque Protein
Registry Number
0
Previous Indexing
Carrier Proteins (1995-2016)
Cytoskeletal Proteins (1995-2016)
Nerve Tissue Proteins (1995-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/04/15
Dystonin Preferred
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