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Patched-1 Receptor MeSH Descriptor Data 2022


MeSH Heading
Patched-1 Receptor
Tree Number(s)
D12.776.543.750.058.500
D12.776.624.776.633.500
Unique ID
D000072081
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000072081
Scope Note
A patched receptor for several HEDGEHOG PROTEINS that associates with the SMOOTHENED RECEPTOR to modulate hedgehog signaling. It is also a TUMOR SUPPRESSOR PROTEIN; mutations in the patched-1 gene are associated with BASAL CELL NEVUS SYNDROME; SQUAMOUS CELL CARCNIOMA of the ESOPHAGUS; trichoepitheliomas, and CARCINOMA, TRANSITIONAL CELL of the URINARY BLADDER.
Entry Term(s)
PTCH1 Protein
Patched Homolog-1
Patched Receptor-1
Patched-1 Protein
Registry Number
0
Public MeSH Note
2017; PATCHED-1 RECEPTOR was indexed under RECEPTORS, CELL SURFACE 2005-2016, and under MEMBRANE PROTEINS 1996-2005
History Note
2017 (1996)
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/05/27
Patched-1 Receptor Preferred
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