NLM Logo

NADPH Oxidase 2 MeSH Descriptor Data 2023


MeSH Heading
NADPH Oxidase 2
Tree Number(s)
D08.811.682.608.575.875
D12.776.331.894.875
D12.776.543.653.875
Unique ID
D000074662
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000074662
Scope Note
An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE.
Entry Term(s)
CYBB Protein
Chronic Granulomatous Disease Protein
Cytochrome B-245 Beta Chain
GP91-PHOX Protein
NOX2 Protein
Registry Number
EC 1.6.3.-
Previous Indexing
Membrane Glycoproteins (1988-2017)
NADPH Oxidases (1997-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2017/04/05
NADPH Oxidase 2 Preferred
page delivered in 0.151s