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Dual Oxidases MeSH Descriptor Data 2024


MeSH Heading
Dual Oxidases
Tree Number(s)
D08.811.682.608.575.500
D12.776.331.894.500
D12.776.543.653.500
Unique ID
D000074623
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000074623
Scope Note
NADPH oxidases that contain two additional EF HAND MOTIFS and an N-terminal PEROXIDASE domain. They are expressed by THYROCYTES and EPITHELIAL CELLS of the kidney, liver, trachea, lung, and glandular tissues such as the testis, pancreas, and prostate. They are critical for the activity of THYROID PEROXIDASE and play a role in the production of thyroid hormones; they may also have antimicrobial activity through the generation of REACTIVE OXYGEN SPECIES.
Entry Term(s)
DUOX1
DUOX2
Dual Oxidase
Dual Oxidase 1
Dual Oxidase 2
Duox Proteins
NADPH Thyroid Oxidase 2
Thyroid Oxidase 2
Registry Number
EC 1.11.1.-
Related Numbers
EC 1.6.3.1
Previous Indexing
NADPH Oxidases (2001-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2020/05/27
Dual Oxidases Preferred
Dual Oxidase 1 Narrower
Dual Oxidase 2 Narrower
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