MeSH Browser

MeSH Heading: Deleted in Azoospermia 1 Protein
Tree Number(s): D12.776.157.725.813.375; D12.776.664.962.813.375
Unique ID: D000075364
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000075364
Scope Note: An RNA recognition motif protein that is essential for SPERMATOGENESIS. It promotes entry of male GERM CELLS to MEIOSIS, possibly by regulating the translation of mRNAs. DAZ1 occurs within a cluster of similar genes on the Y CHROMOSOME that is prone to genetic deletions and duplications. Deletions in these genes, including DAZ1, are associated with AZOOSPERMIA and OLIGOSPERMIA.
Entry Term(s): DAZ-1 Protein; DAZ1 Protein; SPGY Protein
Previous Indexing: RNA-Binding Proteins (1995-2017)
See Also: RNA Recognition Motif
Public MeSH Note: 2018
History Note: 2018
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/05/22

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000630239
Scope Note: An RNA recognition motif protein that is essential for SPERMATOGENESIS. It promotes entry of male GERM CELLS to MEIOSIS, possibly by regulating the translation of mRNAs. DAZ1 occurs within a cluster of similar genes on the Y CHROMOSOME that is prone to genetic deletions and duplications. Deletions in these genes, including DAZ1, are associated with AZOOSPERMIA and OLIGOSPERMIA.
Terms: Deleted in Azoospermia 1 Protein Preferred Term
Term UI T000921915
Date04/18/2017
LexicalTag NON
ThesaurusID NLM (2018); SPGY Protein
Term UI T000921917
Date04/18/2017
LexicalTag ABX
ThesaurusID NLM (2018); DAZ1 Protein
Term UI T000925124
Date05/22/2017
LexicalTag ABX
ThesaurusID NLM (2018); DAZ-1 Protein
Term UI T000925125
Date05/22/2017
LexicalTag ABX
ThesaurusID NLM (2018)

Deleted in Azoospermia 1 Protein MeSH Descriptor Data 2024