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Cell Adhesion Molecule-1 MeSH Descriptor Data 2022


MeSH Heading
Cell Adhesion Molecule-1
Tree Number(s)
D12.776.395.550.200.115
D12.776.543.550.200.128
D23.050.301.350.115
Unique ID
D000075982
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000075982
Scope Note
A cell adhesion molecule that contains extracellular immunoglobulin V and C2 domains. It mediates homophilic and heterophilic cell-cell adhesion independently of calcium, and acts as a tumor suppressor in NON-SMALL-CELL LUNG CANCER (NSCLC) cells. Its interaction with NATURAL KILLER CELLS is important for their cytotoxicity and its expression by MAST CELLS plays a role in their interaction with neurons; it may also function in synapse assembly, nerve growth and differentiation.
Entry Term(s)
CADM1 Protein
IGSF4 Protein
TSLC1 Protein
Tumor Suppressor in Lung Cancer 1 Protein
Registry Number
0
Previous Indexing
Cell Adhesion Molecules (2000-2017)
Immunoglobulins (2000-2017)
See Also
Immunoglobulin Domains
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2017/06/29
Cell Adhesion Molecule-1 Preferred
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