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Decitabine MeSH Descriptor Data 2022


MeSH Heading
Decitabine
Tree Number(s)
D02.145.150.500
D03.383.742.680.245.217.500
D13.570.685.245.217.500
D13.570.800.286.300.500
Unique ID
D000077209
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077209
Scope Note
An azacitidine derivative and antineoplastic antimetabolite. It inhibits DNA methyltransferase to re-activate silent genes, limiting METASTASIS and NEOPLASM DRUG RESISTANCE. Decitabine is used in the treatment of MYELODISPLASTIC SYNDROMES, and ACUTE MYELOID LEUKEMIA.
Entry Term(s)
2'-Deoxy-5-azacytidine
5-Aza-2'-deoxycytidine
5-AzadC
5-Azadeoxycytidine
5-Deoxyazacytidine
5AzadC
AzadC Compound
Dacogen
Decitabine Mesylate
NSC 127716
NSC-127716
Pharm Action
Antimetabolites, Antineoplastic
Enzyme Inhibitors
Registry Number
776B62CQ27
Related Numbers
2353-33-5
6U3LPL9PRN
See Also
Cytarabine
Public MeSH Note
2019; DECITABINE was indexed under AZACITIDINE 1981-2018, and under DEOXYCITIDNE 1977-1980
History Note
2019 (1977)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/07/02
Decitabine Preferred
Dacogen Narrower
5-Deoxyazacytidine Related
NSC 127716 Narrower
Decitabine Mesylate Narrower
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