A carcinoma that originates usually from cells on the surface of the middle and lower third of the ESOPHAGUS. Tumor cells exhibit typical squamous morphology and form large polypoid lesions. Mutations in RNF6, LZTS1, TGFBR2, DEC1, and WWOX1 genes are associated with this cancer.
Entry Term(s)
Oesophageal Squamous Cell Carcinoma
NLM Classification #
WI 260
Public MeSH Note
2019; ESOPHAGEAL SQUAMOUS CELL CARCINOMA was indexed under CARCINOMA, SQUAMOUS CELL and ESOPHAGEAL NEOPLASMS 2012-2018; for OESOPHAGEAL SQUAMOUS CELL CARCINOMA see Squamous CELL CARCINOMA OF HEAD AND NECK 2021
A carcinoma that originates usually from cells on the surface of the middle and lower third of the ESOPHAGUS. Tumor cells exhibit typical squamous morphology and form large polypoid lesions. Mutations in RNF6, LZTS1, TGFBR2, DEC1, and WWOX1 genes are associated with this cancer.