MeSH Browser

MeSH Heading: Vorinostat
Tree Number(s): D02.065.199.960; D02.092.146.113.960; D02.092.570.394.690; D02.241.511.372.690
Unique ID: D000077337
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077337
Scope Note: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
Entry Term(s): 18F-SAHA; 18F-Suberoylanilide Hydroxamic Acid; M344; MK-0683; MK0683; N-Hydroxy-N'-phenyloctanediamide; N1-Hydroxy-N8-phenyloctanediamide; NHNPODA; Suberanilohydroxamic Acid; Suberoyl Anilide Hydroxamic Acid; Suberoylanilide Hydroxamic Acid; Zolinza
Pharm Action: Antineoplastic Agents
Histone Deacetylase Inhibitors
Public MeSH Note: 2019; VORINOSTAT was indexed under HYDROXAMIC ACIDS 1998-2018
History Note: 2019 (1998)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/02/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0288128
Scope Note: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
Terms: Vorinostat Preferred Term
Term UI T000939368
Date01/19/2018
LexicalTag NON
ThesaurusID; N-Hydroxy-N'-phenyloctanediamide
Term UI T000939369
Date01/19/2018
LexicalTag NON
ThesaurusID NLM (1998); N1-Hydroxy-N8-phenyloctanediamide
Term UI T000939370
Date01/19/2018
LexicalTag NON
ThesaurusID NLM (2016); Suberanilohydroxamic Acid
Term UI T000939371
Date01/19/2018
LexicalTag NON
ThesaurusID NLM (2000); Suberoyl Anilide Hydroxamic Acid
Term UI T000939372
Date01/19/2018
LexicalTag NON
ThesaurusID NLM (2017); Suberoylanilide Hydroxamic Acid
Term UI T000939373
Date01/19/2018
LexicalTag NON
ThesaurusID NLM (1998); NHNPODA
Term UI T276171
Date01/01/1955
LexicalTag ABB
ThesaurusID NLM (1998)

Vorinostat MeSH Descriptor Data 2024