MeSH Browser

MeSH Heading: Cidofovir
Tree Number(s): D02.705.429.437; D03.383.742.698.421.216
Unique ID: D000077404
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077404
Scope Note: An acyclic nucleoside phosphonate that acts as a competitive inhibitor of viral DNA polymerases. It is used in the treatment of RETINITIS caused by CYTOMEGALOVIRUS INFECTIONS and may also be useful for treating HERPESVIRUS INFECTIONS.
Entry Term(s): 1-((3-Hydroxy-2-phosphonylmethoxy)propyl)cytosine; 1-(3-Hydroxy-2-phosphonylmethoxypropyl)cytosine; Cidofovir Anhydrous; Cidofovir Sodium; Cidofovir, (+-)-isomer; Cidofovir, (R)-isomer; Cidofovir, Sodium Salt; GS 504; GS-504; HPMPC; Vistide
Pharm Action: Antiviral Agents
Enzyme Inhibitors
Registry Number: JIL713Q00N
Related Numbers: 113852-37-2; 128347-13-7; 768M1V522C; M83JB37U61
CAS Type 1 Name: Phosphonic acid, (((1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy)methyl)-
Public MeSH Note: 2019; CIDOFOVIR was indexed under CYTOSINE/analogs & derivatives 1989-2018; under ORGANOPHOSPHONATES 2005-2018; and under ORGANOPHOSPHORUS COMPOUNDS 1989-2004
History Note: 2019 (1989)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/07/03

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Cidofovir MeSH Descriptor Data 2024