NLM Logo

Angiotensin-Converting Enzyme 2 MeSH Descriptor Data 2024

MeSH Heading
Angiotensin-Converting Enzyme 2
Tree Number(s)
Unique ID
RDF Unique Identifier
Scope Note
A transmembrane glycoprotein with an extracellular catalytic domain which functions as a carboxypeptidase. It cleaves a single C-terminal residue from a distinct range of substrates. The catalytic efficiency is 400-fold higher with ANGIOTENSIN II as a substrate than with ANGIOTENSIN I. Angiotensin-converting enzyme 2 is also is a functional receptor for the spike glycoprotein (SPIKE PROTEIN, CORONAVIRUS) of the CORONAVIRUSES SARS-COV, SARS-COV2, and HCOV-NL63.
Entry Term(s)
ACE-Related Carboxypeptidase
ACE2 Angiotensin-Converting Enzyme Protein 2
ACE2 Enzyme
ACE2 Protein
Angiotensin Converting Enzyme 2
Angiotensin-Converting Enzyme-Related Carboxypeptidase
Registry Number
Public MeSH Note
2021; ACE2 ENZYME was indexed as CARBOXYPEPTIDASES 2000-2006; and PEPTIDYL-DIPEPTIDASE A 2007-2020
History Note
2021 (2000)
Date Established
Date of Entry
Revision Date
Angiotensin-Converting Enzyme 2 Preferred
page delivered in 0.15s