Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

HLA-E Antigens MeSH Descriptor Data 2025


MeSH Heading
HLA-E Antigens
Tree Number(s)
D09.400.430.890.489.850
D12.776.395.550.489.850
D12.776.543.550.439.850
D23.050.301.500.100.850
D23.050.705.552.100.850
Unique ID
D000097625
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000097625
Scope Note
Class I human histocompatibility (HLA) antigens encoded by genes at the E locus on chromosome 6. They bind a restricted subset of peptides derived from the leader peptides of other class I molecules. They primarily are involved with down-regulating cytolytic activity of NK CELLS and restricting non-canonical CD8-POSITIVE T LYMPHOCYTES.
Entry Term(s)
HLA E Antigens
HLA E*0101 antigen
HLA-E 0103 antigen
HLA-E*0101 antigen
HLA-E*0103
HLA-E*01:01 antigen
HLA-E*01:03 antigen
Registry Numbers
0
Public MeSH Note
2024: HLA-E ANTIGEN was indexed under HISTOCOMPATIBILITY ANTIGENS CLASS I 1989-2023, and under HLA ANTIGENS 1988-1988
History Note
2024 (1988)
Date Established
2024/01/01
Date of Entry
2023/07/26
Revision Date
2023/06/14
HLA-E Antigens Preferred
HLA-E*01:03 antigen Narrower
HLA-E*01:01 antigen Narrower
page delivered in 0.132s