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Class I human histocompatibility (HLA) antigens encoded by genes at the E locus on chromosome 6. They bind a restricted subset of peptides derived from the leader peptides of other class I molecules. They primarily are involved with down-regulating cytolytic activity of NK CELLS and restricting non-canonical CD8-POSITIVE T LYMPHOCYTES.
Entry Term(s)
HLA E Antigens
HLA E*0101 antigen
HLA-E 0103 antigen
HLA-E*0101 antigen
HLA-E*0103
HLA-E*01:01 antigen
HLA-E*01:03 antigen
Registry Numbers
0
Public MeSH Note
2024: HLA-E ANTIGEN was indexed under HISTOCOMPATIBILITY ANTIGENS CLASS I 1989-2023, and under HLA ANTIGENS 1988-1988
Class I human histocompatibility (HLA) antigens encoded by genes at the E locus on chromosome 6. They bind a restricted subset of peptides derived from the leader peptides of other class I molecules. They primarily are involved with down-regulating cytolytic activity of NK CELLS and restricting non-canonical CD8-POSITIVE T LYMPHOCYTES.