NLM Logo

beta 2-Microglobulin MeSH Descriptor Data 2022


MeSH Heading
beta 2-Microglobulin
Tree Number(s)
D12.776.124.790.223.100
D12.776.377.715.182.100
D12.776.395.550.489.100
D12.776.543.550.439.100
D23.050.301.500.100.175
D23.050.705.552.100.175
Unique ID
D001613
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D001613
Scope Note
An 11-kDa protein associated with the outer membrane of many cells including LYMPHOCYTES. It is the small subunit of MHC CLASS I MOLECULES. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, CEREBROSPINAL FLUID, and urine of healthy individuals, and to a much greater degree in the urine and plasma of patients with tubular PROTEINURIA, renal failure, or kidney transplants.
Entry Term(s)
Thymotaxin
Registry Number
0
NLM Classification #
WH 400
Previous Indexing
Beta Globulins (1973-1974)
Public MeSH Note
1991; see BETA 2 MICROGLOBULIN 1984-1990; BETA 2-MICROGLOBULIN was indexed under BETA GLOBULINS 1975-1983
History Note
1991 (1975); use BETA 2 MICROGLOBULIN 1984-1990
Date Established
1984/01/01
Date of Entry
1974/11/19
Revision Date
2018/02/01
beta 2-Microglobulin Preferred
page delivered in 0.18s