NLM Logo

Sex Hormone-Binding Globulin MeSH Descriptor Data 2022


MeSH Heading
Sex Hormone-Binding Globulin
Tree Number(s)
D12.776.124.790.223.800
D12.776.157.762
D12.776.377.715.182.800
Unique ID
D012738
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D012738
Annotation
does not refer to all sex hormones: refers to a specific protein in the blood binding only testosterone or estradiol; for other sex hormone-binding globulins consider ANDROGEN-BINDING PROTEIN & PROGESTERONE-BINDING GLOBULIN
Scope Note
A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Sex hormone-binding protein has the same amino acid sequence as ANDROGEN-BINDING PROTEIN. They differ by their sites of synthesis and post-translational oligosaccharide modifications.
Entry Version
SHBG
Entry Term(s)
Sex Steroid-Binding Protein
Testosterone-Estradiol Binding Globulin
Registry Number
0
Previous Indexing
Beta Globulins (1974-1976)
Carrier Proteins (1971-1991)
Glycoproteins (1974-1975)
Protein Binding (1974-1975)
Sex Hormones (1974-1976)
See Also
Androgen-Binding Protein
Public MeSH Note
77; SEX-STEROID-BINDING PROTEIN was indexed under CARRIER PROTEINS 1981-91; ESTRADIOL-BINDING GLOBULIN & TESTOSTERONE-BINDING GLOBULIN were see SEX HORMONE-BINDING GLOBULIN 1977-92
Online Note
use SEX HORMONE-BINDING GLOBULIN (NM) to search SEX-STEROID-BINDING PROTEIN 1981-91; use SEX HORMONE-BINDING GLOBULIN to search ESTRADIOL-BINDING GLOBULIN & TESTOSTERONE-BINDING GLOBULIN 1977-92
History Note
77; SEX STEROID-BINDING PROTEIN was SEX-STEROID-BINDING PROTEIN (NM) 1981-91; ESTRADIOL-BINDING GLOBULIN & TESTOSTERONE-BINDING GLOBULIN were see SEX HORMONE-BINDING GLOBULIN 1977-92
Date Established
1977/01/01
Date of Entry
1976/04/16
Revision Date
2019/05/24
Sex Hormone-Binding Globulin Preferred
page delivered in 0.188s