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Anthramycin MeSH Descriptor Data 2022


MeSH Heading
Anthramycin
Tree Number(s)
D03.633.100.079.080.070.050
D03.633.300.060
Unique ID
D000876
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000876
Scope Note
A broad-spectrum spectrum antineoplastic antibiotic isolated from Streptomyces refuineus var. thermotolerans. It has low toxicity, some activity against Trichomonas and Endamoeba, and inhibits RNA and DNA synthesis. It binds irreversibly to DNA.
Entry Term(s)
Anthramycin, (11a alpha)-Isomer
Antramycin
Pharm Action
Antibiotics, Antineoplastic
Registry Number
0WZD9Y66WN
Related Numbers
35599-87-2
4803-27-4
CAS Type 1 Name
2-Propenamide, 3-(5,10,11,11a-tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1H-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-, (11R-(2(E),11alpha,11abeta))-
Previous Indexing
Acrylamides (1973-1974)
Benzodiazepinones (1974)
Pyrroles (1972-1974)
Public MeSH Note
91; was see under BENZODIAZEPINONES 1975-90
History Note
91(75); was see under BENZODIAZEPINONES 1975-90
Date Established
1991/01/01
Date of Entry
1974/11/11
Revision Date
2016/05/27
Anthramycin Preferred
Anthramycin, (11a alpha)-Isomer Narrower
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