MeSH Browser

MeSH Heading: Pirenzepine
Tree Number(s): D03.633.100.079.080.070.750
Unique ID: D010890
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D010890
Scope Note: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Entry Term(s): Gastrotsepin; Gastrozepin; L-S 519; LS-519; Piren-Basan; Pirenzepin; Pirenzepin Von Ct; Pirenzepin-Ratiopharm; Pirenzepine Dihydrochloride; Pyrenzepine; Ulcoprotect; Ulgescum
Pharm Action: Anti-Ulcer Agents
Muscarinic Antagonists
Related Numbers: 10YM403FLS; 28797-61-7
CAS Type 1 Name: 6H-Pyrido(2,3-b)(1,4)benzodiazepin-6-one, 5,11-dihydro-11-((4-methyl-1-piperazinyl)acetyl)-
Previous Indexing: Azepines (1966-1973); Benzodiazepinones (1974-1986)
Public MeSH Note: 87
History Note: 87
Date Established: 1987/01/01
Date of Entry: 1986/04/09
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0016894
Related Numbers: 10YM403FLS; 28797-61-7
Scope Note: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Terms: Pirenzepine Preferred Term
Term UI T032096
Date01/01/1999
LexicalTag NON
ThesaurusID; Pirenzepin
Term UI T032097
Date04/09/1986
LexicalTag NON
ThesaurusID UNK (19XX); Pyrenzepine
Term UI T032098
Date04/09/1986
LexicalTag NON
ThesaurusID UNK (19XX)

Pirenzepine MeSH Descriptor Data 2024