MeSH Browser

MeSH Heading: Cimetidine
Tree Number(s): D02.078.370.200; D03.383.129.308.130
Unique ID: D002927
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D002927
Scope Note: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
Entry Term(s): Altramet; Biomet; Biomet400; Cimetidine HCl; Cimetidine Hydrochloride; Eureceptor; Histodil; N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine; SK&F-92334; SKF-92334; Tagamet
Pharm Action: Anti-Ulcer Agents
Histamine H2 Antagonists
Cytochrome P-450 CYP1A2 Inhibitors
Registry Numbers: 80061L1WGD; 0; WF10491673
Related Numbers: 51481-61-9; 70059-30-2; WF10491673
CAS Type 1 Name: Guanidine, N-cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)-
NLM Classification #: QV 157
Previous Indexing: Guanidines (1966-1977); Imidazoles (1966-1977)
Public MeSH Note: 84; was see under GUANIDINES 1978-83
History Note: 84(78); was see under GUANIDINES 1978-83
Date Established: 1984/01/01
Date of Entry: 1977/04/22
Revision Date: 2016/05/28

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Cimetidine MeSH Descriptor Data 2025