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Clotrimazole MeSH Descriptor Data 2022


MeSH Heading
Clotrimazole
Tree Number(s)
D03.383.129.308.175
Unique ID
D003022
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D003022
Scope Note
An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal CELL MEMBRANES. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane.
Entry Term(s)
Bay b 5097
Canesten
FB b 5097
Kanesten
Klotrimazole
Lotrimin
Mycelex
Pharm Action
Anti-Infective Agents, Local
Antifungal Agents
14-alpha Demethylase Inhibitors
Registry Number
G07GZ97H65
Related Numbers
23593-75-1
CAS Type 1 Name
1H-Imidazole, 1-((2-chlorophenyl)diphenylmethyl)-
Previous Indexing
Imidazoles (1971-1974)
Trityl Compounds (1974)
Public MeSH Note
91; was see under IMIDAZOLES 1975-90
History Note
91(75); was see under IMIDAZOLES 1975-90
Date Established
1991/01/01
Date of Entry
1974/11/11
Revision Date
2017/05/24
Clotrimazole Preferred
Mycelex Narrower
FB b 5097 Narrower
Lotrimin Narrower
Bay b 5097 Narrower
Canesten Narrower
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