MeSH Browser

MeSH Heading: 14-alpha Demethylase Inhibitors
Tree Number(s): D27.505.389.500.059; D27.505.519.389.335.059; D27.505.519.389.870.100; D27.505.696.399.450.855.100
Unique ID: D058888
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D058888
Scope Note: Compounds that specifically inhibit STEROL 14-DEMETHYLASE. A variety of azole-derived ANTIFUNGAL AGENTS act through this mechanism.
Entry Term(s): 14alpha-Demethylase Inhibitors; CYP51 Inhibitors; Lanosterol 14 alpha-Demethylase Inhibitors
Public MeSH Note: 2011
History Note: 2011
Date Established: 2011/01/01
Date of Entry: 2010/06/25
Revision Date: 2014/06/25

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0545196
Scope Note: Compounds that specifically inhibit STEROL 14-DEMETHYLASE. A variety of azole-derived ANTIFUNGAL AGENTS act through this mechanism.
Terms: 14-alpha Demethylase Inhibitors Preferred Term
Term UI T768715
Date04/06/2010
LexicalTag NON
ThesaurusID NLM (2011); 14alpha-Demethylase Inhibitors
Term UI T768718
Date04/06/2010
LexicalTag NON
ThesaurusID NLM (2011); CYP51 Inhibitors
Term UI T768717
Date04/06/2010
LexicalTag ABX
ThesaurusID NLM (2011); Lanosterol 14 alpha-Demethylase Inhibitors
Term UI T768716
Date04/06/2010
LexicalTag NON
ThesaurusID NLM (2011)

14-alpha Demethylase Inhibitors MeSH Descriptor Data 2024