MeSH Browser

MeSH Heading: Methimazole
Tree Number(s): D02.886.489.600; D03.383.129.308.535
Unique ID: D008713
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D008713
Scope Note: A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.
Entry Term(s): 1-Methyl-2-mercaptoimidazole; Favistan; Mercasolyl; Mercazol; Mercazole; Mercazolyl; Merkazolil; Methizol; Methylmercaptoimidazole; Methymazol; Metisol; Metizol; Strumazol; Tapazole; Thiamazol Henning; Thiamazol Hexal; Thiamazole; Thimazol; Thyrozol; Tiamazol; Tirodril
Pharm Action: Antithyroid Agents
Registry Numbers: 554Z48XN5E; 0
Related Numbers: 60-56-0
CAS Type 1 Name: 2H-Imidazole-2-thione, 1,3-dihydro-1-methyl-
Previous Indexing: Imidazoles (1966-1967); Thyroid Antagonists (1966-1967)
Public MeSH Note: 73; was see under THYROID ANTAGONISTS 1963-72
Online Note: search THYROID ANTAGONISTS 1966-67
History Note: 73(68); was see under THYROID ANTAGONISTS 1963-72
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0013573
Registry Numbers: 554Z48XN5E
Related Numbers: 60-56-0
Scope Note: A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.
Terms: Methimazole Preferred Term
Term UI T025924
Date01/01/1999
LexicalTag NON
ThesaurusID; Methymazol
Term UI T025933
Date12/31/1976
LexicalTag NON
ThesaurusID UNK (19XX); 1-Methyl-2-mercaptoimidazole
Term UI T025920
Date06/09/1989
LexicalTag NON
ThesaurusID NLM (1990); Merkazolil
Term UI T025923
Date10/07/1986
LexicalTag NON
ThesaurusID UNK (19XX); Methylmercaptoimidazole
Term UI T025925
Date07/28/1981
LexicalTag NON
ThesaurusID UNK (19XX); Thiamazole
Term UI T025927
Date12/31/1976
LexicalTag NON
ThesaurusID; Thimazol
Term UI T025929
Date03/05/1981
LexicalTag NON
ThesaurusID UNK (19XX); Mercasolyl
Term UI T025930
Date10/09/1986
LexicalTag NON
ThesaurusID UNK (19XX); Tiamazol
Term UI T025935
Date07/28/1981
LexicalTag NON
ThesaurusID UNK (19XX); Mercazolyl
Term UI T025932
Date06/04/1981
LexicalTag NON
ThesaurusID UNK (19XX)

Methimazole MeSH Descriptor Data 2024