MeSH Browser

MeSH Heading: Mesna
Tree Number(s): D02.455.326.146.100.050.490; D02.886.489.590; D02.886.645.600.055.050.500
Unique ID: D015080
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015080
Scope Note: A sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from ANTINEOPLASTIC AGENTS, such as IFOSFAMIDE or CYCLOPHOSPHAMIDE.
Entry Term(s): 2-Mercaptoethanesulfonate; ASTA-D 7093; Coenzyme M; Ethanesulfonic acid, 2-mercapto-, monosodium salt; MESNA-cell; Mesnex; Mesnum; Mistabron; Mistabronco; Mitexan; Mucofluid; Sodium 2-Mercaptoethanesulphonate; UCB-3983; Uromitexan; Ziken
Pharm Action: Protective Agents
Registry Number: NR7O1405Q9
Related Numbers: 19767-45-4; 3375-50-6
Previous Indexing: Alkyl Sulfonates (1974-1975); Mercaptoethanol (1974-1976)
Public MeSH Note: 92; was 2-MERCAPTOETHANESULFONATE 1977-91 (see under MERCAPTOETHANOL 1977-90); MESNA was see 2-MERCAPTOETHANESULFONATE 1978-91
Online Note: use MESNA to search 2-MERCAPTOETHANESULFONATE 1977-91
History Note: 92; was 2-MERCAPTOETHANESULFONATE 1977-91 (see under MERCAPTOETHANOL 1977-90); MESNA was see 2-MERCAPTOETHANESULFONATE 1978-91
Date Established: 1991/01/01
Date of Entry: 1976/04/16
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0023193
Registry Number: NR7O1405Q9
Related Numbers: 19767-45-4; 3375-50-6
Scope Note: A sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from ANTINEOPLASTIC AGENTS, such as IFOSFAMIDE or CYCLOPHOSPHAMIDE.
Terms: Mesna Preferred Term
Term UI T043993
Date01/01/1999
LexicalTag NON
ThesaurusID; Mesnum
Term UI T043992
Date08/18/1980
LexicalTag NON
ThesaurusID UNK (19XX); Sodium 2-Mercaptoethanesulphonate
Term UI T043998
Date02/24/1998
LexicalTag NON
ThesaurusID; Ethanesulfonic acid, 2-mercapto-, monosodium salt
Term UI T001081011
Date05/20/2020
LexicalTag NON
ThesaurusID NLM (2021)

Mesna MeSH Descriptor Data 2024