MeSH Browser

MeSH Heading: 3-Iodobenzylguanidine
Tree Number(s): D02.078.370.510; D02.455.426.559.389.454.300; D02.455.526.581.496.300
Unique ID: D019797
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019797
Scope Note: A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.
Entry Term(s): (3-Iodo-(131I)benzyl)guanidine; 3-Iodobenzylguanidine, 123I Labeled; 3-Iodobenzylguanidine, 125I Labeled; Iobenguane; Iobenguane (131I); MIBG; m-Iodobenzylguanidine; meta-Iodobenzylguanidine
Pharm Action: Antineoplastic Agents
Enzyme Inhibitors
Radiopharmaceuticals
Registry Numbers: 35MRW7B4AD; 0; Q461L7AK4R; 74075-13-1; 76924-93-1
Related Numbers: 74075-13-1; 76924-93-1; 77679-27-7; Q461L7AK4R
Previous Indexing: Guanidines (1980-1982); Iodobenzenes (1983-1997)
Public MeSH Note: 98; 3-IODOBENZYLGUANIDINE was indexed under IODOBENZENES 1983-97 & GUANIDINES 1980-82
History Note: 98; use 3-IODOBENZYLGUANIDINE (NM) 1980-97
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0029373
Registry Numbers: 35MRW7B4AD
Related Numbers: 74075-13-1; 76924-93-1; 77679-27-7; Q461L7AK4R
Scope Note: A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.
Terms: 3-Iodobenzylguanidine Preferred Term
Term UI T058883
Date01/01/1999
LexicalTag NON
ThesaurusID; Iobenguane
Term UI T058887
Date12/27/1996
LexicalTag NON
ThesaurusID; m-Iodobenzylguanidine
Term UI T058884
Date12/27/1996
LexicalTag NON
ThesaurusID; meta-Iodobenzylguanidine
Term UI T058885
Date12/27/1996
LexicalTag NON
ThesaurusID NLM (1998); MIBG
Term UI T058886
Date12/19/1996
LexicalTag ABB
ThesaurusID

3-Iodobenzylguanidine MeSH Descriptor Data 2024