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Arnold-Chiari Malformation MeSH Descriptor Data 2025


MeSH Heading
Arnold-Chiari Malformation
Tree Number(s)
C10.500.680.291
C16.131.666.680.291
Unique ID
D001139
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D001139
Annotation
do not confuse with CHIARI'S SYNDROME see BUDD-CHIARI SYNDROME
Scope Note
A group of congenital malformations involving the brainstem, cerebellum, upper spinal cord, and surrounding bony structures. Type II is the most common, and features compression of the medulla and cerebellar tonsils into the upper cervical spinal canal and an associated MENINGOMYELOCELE. Type I features similar, but less severe malformations and is without an associated meningomyelocele. Type III has the features of type II with an additional herniation of the entire cerebellum through the bony defect involving the foramen magnum, forming an ENCEPHALOCELE. Type IV is a form a cerebellar hypoplasia. Clinical manifestations of types I-III include TORTICOLLIS; opisthotonus; HEADACHE; VERTIGO; VOCAL CORD PARALYSIS; APNEA; NYSTAGMUS, CONGENITAL; swallowing difficulties; and ATAXIA. (From Menkes, Textbook of Child Neurology, 5th ed, p261; Davis, Textbook of Neuropathology, 2nd ed, pp236-46)
Entry Term(s)
Arnold-Chiari Deformity
Arnold-Chiari Malformation, Type 1
Arnold-Chiari Malformation, Type 2
Arnold-Chiari Malformation, Type 3
Arnold-Chiari Malformation, Type 4
Arnold-Chiari Malformation, Type I
Arnold-Chiari Malformation, Type II
Arnold-Chiari Malformation, Type III
Arnold-Chiari Malformation, Type IV
Arnold-Chiari Syndrome
Chiari Malformation Type 2
Chiari Malformation Type I
Chiari Malformation Type II
Malformation, Arnold-Chiari
Type I Arnold-Chiari Malformation
Type II Arnold-Chiari Malformation
Type III Arnold-Chiari Malformation
Type IV Arnold-Chiari Malformation
NLM Classification #
WL 101
Public MeSH Note
2000; see ARNOLD-CHIARI DEFORMITY 1963-1999; for ARNOLD-CHIARI MALFORMATION see ARNOLD-CHIARI DEFORMITY 1963-1999
History Note
2000(1963)
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2014/06/13
Arnold-Chiari Malformation Preferred
Arnold-Chiari Malformation, Type I Narrower
Arnold-Chiari Malformation, Type II Narrower
Arnold-Chiari Malformation, Type III Narrower
Arnold-Chiari Malformation, Type IV Narrower
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