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Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)
Entry Term(s)
Acrania
Craniorachischisis
Developmental Defects, Neural Tube
Developmental Neural Tube Defects
Diastematomyelia
Exencephaly
Iniencephaly
Neural Tube Developmental Defects
Neurenteric Cyst
Neuroenteric Cyst
Occult Spinal Dysraphism
Occult Spinal Dysraphism Sequence
Spinal Cord Myelodysplasia
Tethered Cord Syndrome
Tethered Spinal Cord Syndrome
Previous Indexing
Anencephaly (1966-1978)
Central Nervous System (1966-1978)
Spina Bifida (1966-1978)
Public MeSH Note
1979; for DIASTEMATOMYELIA and TETHERED CORD SYNDROME see SPINA BIFIDA OCCULTA 1991-1999; for NEURENTERIC CYST see SPINA BIFIDA OCCULTA 1991-1999, see NEURAL TUBE DEFECTS 1979-1990
History Note
1979; for DIASTEMATOMYELIA and TETHERED CORD SYNDROME use SPINA BIFIDA OCCULTA 1991-1999; for NEURENTERIC CYST use SPINA BIFIDA OCCULTA 1991-1999, use NEURAL TUBE DEFECTS 1979-1990
Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)