MeSH Browser

MeSH Heading: Carmustine
Tree Number(s): D02.065.950.594.247; D02.654.692.247
Unique ID: D002330
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D002330
Scope Note: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
Entry Term(s): 1,3-Bis(2-Chloroethyl)-1-Nitrosourea; BCNU; BiCNU; FIVB; N,N'-Bis(2-Chloroethyl)-N-Nitrosourea; Nitrumon
Pharm Action: Antineoplastic Agents, Alkylating
Related Numbers: 154-93-8
CAS Type 1 Name: Urea, N,N'-bis(2-chloroethyl)-N-nitroso-
Previous Indexing: Alkylating Agents (1966-1971); Nitroso Compounds (1966-1971); Urea (1966-1971)
Public MeSH Note: 73
History Note: 73(72)
Date Established: 1973/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0003490
Related Numbers: 154-93-8
Scope Note: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)
Terms: Carmustine Preferred Term
Term UI T006696
Date01/01/1999
LexicalTag NON
ThesaurusID; 1,3-Bis(2-Chloroethyl)-1-Nitrosourea
Term UI T006694
Date09/17/1981
LexicalTag NON
ThesaurusID; BCNU
Term UI T006695
Date03/29/1974
LexicalTag ABB
ThesaurusID; FIVB
Term UI T006697
Date12/18/1981
LexicalTag ABB
ThesaurusID UNK (19XX); N,N'-Bis(2-Chloroethyl)-N-Nitrosourea
Term UI T006698
Date04/27/1981
LexicalTag NON
ThesaurusID UNK (19XX)

Carmustine MeSH Descriptor Data 2024