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Dimethylallyltranstransferase MeSH Descriptor Data 2022


MeSH Heading
Dimethylallyltranstransferase
Tree Number(s)
D08.811.913.225.400
Unique ID
D004122
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004122
Scope Note
An enzyme that, in the pathway of cholesterol biosynthesis, catalyzes the condensation of isopentenyl pyrophosphate and dimethylallylpyrophosphate to yield pyrophosphate and geranylpyrophosphate. The enzyme then catalyzes the condensation of the latter compound with another molecule of isopentenyl pyrophosphate to yield pyrophosphate and farnesylpyrophosphate. EC 2.5.1.1.
Entry Term(s)
Dimethylallyltransferase
Dolichyl Phosphate Synthetase
Geranylgeranyl Pyrophosphate Synthetase
Geranylpyrophosphate Synthetase
Nerylpyrophosphate Synthetase
Prenyltransferase
Registry Number
EC 2.5.1.1
Related Numbers
9032-79-5
CAS Type 1 Name
Dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyl (trans) transferase
Previous Indexing
Allyl Compounds (1971-1978)
Transferases (1966-1978)
Public MeSH Note
97; was DIMETHYLALLYLTRANSFERASE 1979-96 (see under TRANSFERASES 1979-90)
History Note
97; was DIMETHYLALLYLTRANSFERASE 1979-96 (see under TRANSFERASES 1979-90)
Date Established
1991/01/01
Date of Entry
1978/05/18
Revision Date
2014/06/13
Dimethylallyltranstransferase Preferred
Geranylgeranyl Pyrophosphate Synthetase Related
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