NLM Logo

DNA Polymerase II MeSH Descriptor Data 2024


MeSH Heading
DNA Polymerase II
Tree Number(s)
D08.811.913.696.445.308.300.230
Unique ID
D004257
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004257
Scope Note
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms. It may be present in higher organisms and has an intrinsic molecular activity only 5% of that of DNA Polymerase I. This polymerase has 3'-5' exonuclease activity, is effective only on duplex DNA with gaps or single-strand ends of less than 100 nucleotides as template, and is inhibited by sulfhydryl reagents.
Entry Term(s)
DNA Pol II
DNA Polymerase epsilon
DNA-Dependent DNA Polymerase II
Registry Number
EC 2.7.7.7
Previous Indexing
DNA Nucleotidyltransferases (1968-1976)
Public MeSH Note
84; see DNA POLYMERASES 1977-83; DNA POLYMERASE EPSILON was indexed under DNA POLYMERASES 1994-97
History Note
84(77); for DNA POLYMERASE EPSILON use DNA POLYMERASE II (NM) 1994-97
Date Established
1984/01/01
Date of Entry
1976/04/21
Revision Date
2020/06/22
DNA Polymerase II Preferred
page delivered in 0.151s