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DNA Polymerase iota MeSH Descriptor Data 2024


MeSH Heading
DNA Polymerase iota
Tree Number(s)
D08.811.913.696.445.308.300.493
Unique ID
D000094769
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000094769
Scope Note
A highly error-prone DNA polymerase. It is a member of the Y-family of DNA polymerases that are DNA DAMAGE tolerant and involved in TRANSLESION DNA SYNTHESIS. DNA polymerase iota is an orthologue of yeast Rad30. Its replication fidelity is template dependent and favors Hoogsteen base-pairing at its active site.
Entry Term(s)
POL iota
POLiota
RAD30B
Public MeSH Note
2023; was indexed as DNA-DIRECTED DNA POLYMERASE 2000-2022
History Note
2023 (2000)
Date Established
2023/01/01
Date of Entry
2022/07/13
Revision Date
2023/05/26
DNA Polymerase iota Preferred
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