MeSH Browser

MeSH Heading: Epilepsy, Tonic-Clonic
Tree Number(s): C10.228.140.490.375.290
Unique ID: D004830
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D004830
Annotation: do not confuse with EPILEPSY, TONIC see EPILEPSY, GENERALIZED
Scope Note: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
Entry Term(s): Convulsions, Grand Mal; Cryptogenic Tonic-Clonic Epilepsy; Epilepsy, Grand Mal; Epilepsy, Major; Epilepsy, Tonic-Clonic, Cryptogenic; Epilepsy, Tonic-Clonic, Familial; Epilepsy, Tonic-Clonic, Symptomatic; Familial Tonic-Clonic Epilepsy; Grand Mal Seizure Disorder; Major Motor Seizure Disorder; Seizure Disorder, Grand Mal; Seizure Disorder, Major Motor; Seizure Disorder, Tonic Clonic; Symptomatic Tonic-Clonic Epilepsy; Tonic Clonic Convulsions; Tonic-Clonic Convulsion Disorder; Tonic-Clonic Convulsion Syndrome; Tonic-Clonic Seizure Disorder; Tonic-Clonic Seizure Syndrome
NLM Classification #: WL 385
Public MeSH Note: 1992; see EPILEPSY, GRAND MAL 1963-1991
History Note: 1992(1963)
Date Established: 1992/01/01
Date of Entry: 1999/01/01
Revision Date: 2005/07/30

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
  - Brain Diseases [C10.228.140]
    - Epilepsy [C10.228.140.490]
      - Epilepsy, Generalized [C10.228.140.490.375]
        
        Epilepsies, Myoclonic [C10.228.140.490.375.130]
        
        Epilepsy, Absence [C10.228.140.490.375.260]
        
        Epilepsy, Tonic-Clonic [C10.228.140.490.375.290]
        
        Nodding Syndrome [C10.228.140.490.375.525]
        
        Spasms, Infantile [C10.228.140.490.375.760]

Epilepsy, Tonic-Clonic Preferred

Concept UI: M0007573
Scope Note: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
Terms: Epilepsy, Tonic-Clonic Preferred Term
Term UI T014725
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1966); Epilepsy, Grand Mal
Term UI T014724
Date04/04/1991
LexicalTag NON
ThesaurusID NLM (1992); Epilepsy, Major
Term UI T368056
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Grand Mal Seizure Disorder
Term UI T368057
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Major Motor Seizure Disorder
Term UI T368058
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Tonic-Clonic Seizure Syndrome
Term UI T368080
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Seizure Disorder, Major Motor
Term UI T368074
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Seizure Disorder, Tonic Clonic
Term UI T368059
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Tonic Clonic Convulsions
Term UI T368076
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Tonic-Clonic Convulsion Disorder
Term UI T368077
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Tonic-Clonic Convulsion Syndrome
Term UI T368078
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Tonic-Clonic Seizure Disorder
Term UI T368079
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Convulsions, Grand Mal
Term UI T368060
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000); Seizure Disorder, Grand Mal
Term UI T368073
Date11/03/1999
LexicalTag NON
ThesaurusID NLM (2000)

Epilepsy, Tonic-Clonic, Symptomatic Narrower

Cryptogenic Tonic-Clonic Epilepsy Narrower

Epilepsy, Tonic-Clonic, Familial Narrower

Epilepsy, Tonic-Clonic MeSH Descriptor Data 2024