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Hemicholinium 3 MeSH Descriptor Data 2022


MeSH Heading
Hemicholinium 3
Tree Number(s)
D02.092.877.435
D02.675.276.435
Unique ID
D006426
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D006426
Scope Note
A potent inhibitor of the high affinity uptake system for CHOLINE. It has less effect on the low affinity uptake system. Since choline is one of the components of ACETYLCHOLINE, treatment with hemicholinium can deplete acetylcholine from cholinergic terminals. Hemicholinium 3 is commonly used as a research tool in animal and in vitro experiments.
Entry Term(s)
Hemicholinium
Pharm Action
Neurotransmitter Uptake Inhibitors
Cholinergic Agents
Registry Number
312-45-8
CAS Type 1 Name
Morpholinium, 2,2'-(1,1'-biphenyl)-4,4'-diylbis(2-hydroxy-4,4-dimethyl)-, dibromide
Previous Indexing
Morpholines (1966-1971)
Public MeSH Note
72
History Note
72
Date Established
1972/01/01
Date of Entry
1999/01/01
Revision Date
2005/06/30
Hemicholinium 3 Preferred
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