MeSH Browser

MeSH Heading: Neostigmine
Tree Number(s): D02.092.877.674.666; D02.675.276.602
Unique ID: D009388
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009388
Scope Note: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
Entry Term(s): Neostigmine Bromide; Neostigmine Methylsulfate; Polstigmine; Proserine; Prostigmin; Prostigmine; Prozerin; Synstigmin; Syntostigmine
Pharm Action: Cholinesterase Inhibitors
Parasympathomimetics
Registry Numbers: 3982TWQ96G; 98IMH7M386; 0; 005SYP50G5
Related Numbers: 005SYP50G5; 114-80-7; 51-60-5; 59-99-4; 98IMH7M386
CAS Type 1 Name: Benzenaminium, 3-(((dimethylamino)carbonyl)oxy)-N,N,N-trimethyl-
NLM Classification #: QV 124
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0014615
Registry Numbers: 3982TWQ96G
Related Numbers: 005SYP50G5; 114-80-7; 51-60-5; 59-99-4; 98IMH7M386
Scope Note: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
Terms: Neostigmine Preferred Term
Term UI T028009
Date01/01/1999
LexicalTag NON
ThesaurusID; Prozerin
Term UI T028010
Date11/20/1980
LexicalTag NON
ThesaurusID UNK (19XX); Synstigmin
Term UI T028011
Date12/24/1976
LexicalTag NON
ThesaurusID UNK (19XX); Proserine
Term UI T028012
Date08/04/1980
LexicalTag NON
ThesaurusID UNK (19XX)

Neostigmine MeSH Descriptor Data 2025