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Histiocytosis, Langerhans-Cell MeSH Descriptor Data 2025
A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.
Entry Term(s)
Hand-Schueller-Christian Disease
Hand-Schueller-Christian Syndrome
Hand-Schüller-Christian Disease
Hand-Schüller-Christian Syndrome
Hashimoto-Pritzger Disease
Histiocytosis X
Histiocytosis, Generalized
Histiocytosis-X
Langerhans Cell Granulomatosis
Langerhans Cell Granulomatosis, Pulmonary
Langerhans Cell Histiocytosis
Langerhans-Cell Granulomatosis
Langerhans-Cell Histiocytosis
Letterer-Siwe Disease
Non-Lipid Reticuloendotheliosis
Pulmonary Histiocytosis X
Pulmonary Langerhans Cell Granulomatosis
Schueller-Christian Disease
Systemic Aleukemic Reticuloendotheliosis
Type 2 Histiocytosis
NLM Classification #
WH 720
Previous Indexing
Reticuloendotheliosis (1966-1974)
Public MeSH Note
90; was see under RETICULOENDOTHELIOSIS 1965-75; was HISTIOCYTOSIS X 1975-89
Online Note
use HISTIOCYTOSIS, LANGERHANS-CELL to search HISTIOCYTOSIS X 1975-89; use RETICULOENDOTHELIOSIS 1966-74
History Note
90(75); was see under RETICULOENDOTHELIOSIS 1966-75; was HISTIOCYTOSIS X 1975-89
A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.