MeSH Browser

MeSH Heading: Immunoglobulin epsilon-Chains
Tree Number(s): D12.776.124.486.485.114.619.312.500; D12.776.124.486.485.705.500.370; D12.776.124.790.651.114.619.312.500; D12.776.124.790.651.705.500.370; D12.776.377.715.548.114.619.312.500; D12.776.377.715.548.705.500.370
Unique ID: D007139
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D007139
Annotation: gammopathy: coordinate IMMUNOGLOBULIN EPSILON-CHAINS (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA (IM) or HEAVY CHAIN DISEASE (IM), follow text; DF: IG EPSILON CHAIN
Scope Note: The class of heavy chains found in IMMUNOGLOBULIN E. They have a molecular weight of approximately 72 kDa and they contain about 550 amino acid residues arranged in five domains and about three times more carbohydrate than the heavy chains of IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; and IMMUNOGLOBULIN G.
Entry Version: IG EPSILON CHAINS
Entry Term(s): Ig epsilon Chains; Immunoglobulin epsilon-Chain; Immunoglobulins, epsilon-Chain; epsilon-Chain Immunoglobulins; epsilon-Immunoglobulin Heavy Chain; epsilon-Immunoglobulin Heavy Chains
Pharm Action: Immunologic Factors
Registry Number: 0
Previous Indexing: IgE (1973-1975); Immunoglobulin Fragments (1973-1975); Immunoglobulins, Heavy Chain (1975)
Public MeSH Note: 2006; see IMMUNOGLOBULINS, EPSILON-CHAIN 1992-2005, see IMMUNOGLOBULINS, EPSILON CHAIN 1991, see IMMUNOGLOBULINS, HEAVY CHAIN 1976-1990
History Note: 2006 (1976)
Date Established: 1991/01/01
Date of Entry: 1975/07/18
Revision Date: 2019/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Immunoproteins [D12.776.124.486]
      - Immunoglobulins [D12.776.124.486.485]
        
        Antibodies [D12.776.124.486.485.114]
        
        Immunoglobulin Isotypes [D12.776.124.486.485.114.619]
        
        Immunoglobulin E [D12.776.124.486.485.114.619.312]
        
        Immunoglobulin epsilon-Chains [D12.776.124.486.485.114.619.312.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Immunoproteins [D12.776.124.486]
      - Immunoglobulins [D12.776.124.486.485]
        
        Immunoglobulin Subunits [D12.776.124.486.485.705]
        
        Immunoglobulin Heavy Chains [D12.776.124.486.485.705.500]
        
        Immunoglobulin alpha-Chains [D12.776.124.486.485.705.500.350]
        
        Immunoglobulin delta-Chains [D12.776.124.486.485.705.500.360]
        
        Immunoglobulin epsilon-Chains [D12.776.124.486.485.705.500.370]
        
        Immunoglobulin gamma-Chains [D12.776.124.486.485.705.500.380]
        
        Immunoglobulin mu-Chains [D12.776.124.486.485.705.500.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Serum Globulins [D12.776.124.790]
      - Immunoglobulins [D12.776.124.790.651]
        
        Antibodies [D12.776.124.790.651.114]
        
        Immunoglobulin Isotypes [D12.776.124.790.651.114.619]
        
        Immunoglobulin E [D12.776.124.790.651.114.619.312]
        
        Immunoglobulin epsilon-Chains [D12.776.124.790.651.114.619.312.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Serum Globulins [D12.776.124.790]
      - Immunoglobulins [D12.776.124.790.651]
        
        Immunoglobulin Subunits [D12.776.124.790.651.705]
        
        Immunoglobulin Heavy Chains [D12.776.124.790.651.705.500]
        
        Immunoglobulin alpha-Chains [D12.776.124.790.651.705.500.350]
        
        Immunoglobulin delta-Chains [D12.776.124.790.651.705.500.360]
        
        Immunoglobulin epsilon-Chains [D12.776.124.790.651.705.500.370]
        
        Immunoglobulin gamma-Chains [D12.776.124.790.651.705.500.380]
        
        Immunoglobulin mu-Chains [D12.776.124.790.651.705.500.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Globulins [D12.776.377]
    - Serum Globulins [D12.776.377.715]
      - Immunoglobulins [D12.776.377.715.548]
        
        Antibodies [D12.776.377.715.548.114]
        
        Immunoglobulin Isotypes [D12.776.377.715.548.114.619]
        
        Immunoglobulin E [D12.776.377.715.548.114.619.312]
        
        Immunoglobulin epsilon-Chains [D12.776.377.715.548.114.619.312.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Globulins [D12.776.377]
    - Serum Globulins [D12.776.377.715]
      - Immunoglobulins [D12.776.377.715.548]
        
        Immunoglobulin Subunits [D12.776.377.715.548.705]
        
        Immunoglobulin Heavy Chains [D12.776.377.715.548.705.500]
        
        Immunoglobulin alpha-Chains [D12.776.377.715.548.705.500.350]
        
        Immunoglobulin delta-Chains [D12.776.377.715.548.705.500.360]
        
        Immunoglobulin epsilon-Chains [D12.776.377.715.548.705.500.370]
        
        Immunoglobulin gamma-Chains [D12.776.377.715.548.705.500.380]
        
        Immunoglobulin mu-Chains [D12.776.377.715.548.705.500.500]

Immunoglobulin epsilon-Chains Preferred

Concept UI: M0011125
Registry Number: 0
Scope Note: The class of heavy chains found in IMMUNOGLOBULIN E. They have a molecular weight of approximately 72 kDa and they contain about 550 amino acid residues arranged in five domains and about three times more carbohydrate than the heavy chains of IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; and IMMUNOGLOBULIN G.
Terms: Immunoglobulin epsilon-Chains Preferred Term
Term UI T634009
Date03/22/2005
LexicalTag NON
ThesaurusID NLM (2006); epsilon-Chain Immunoglobulins
Term UI T021379
Date01/01/1986
LexicalTag NON
ThesaurusID UNK (19XX); Immunoglobulins, epsilon-Chain
Term UI T021380
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1976); epsilon-Immunoglobulin Heavy Chains
Term UI T634011
Date03/22/2005
LexicalTag NON
ThesaurusID NLM (2006); Immunoglobulin epsilon-Chain
Term UI T634010
Date03/22/2005
LexicalTag NON
ThesaurusID NLM (2006); Ig epsilon Chains
Term UI T000952300
Date03/01/2019
LexicalTag NON
ThesaurusID NLM (2020); epsilon-Immunoglobulin Heavy Chain
Term UI T634012
Date03/22/2005
LexicalTag NON
ThesaurusID NLM (2006)

Immunoglobulin epsilon-Chains MeSH Descriptor Data 2024