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Immunoglobulin gamma-Chains MeSH Descriptor Data 2022


MeSH Heading
Immunoglobulin gamma-Chains
Tree Number(s)
D12.776.124.486.485.114.619.393.522
D12.776.124.486.485.705.500.380
D12.776.124.790.651.114.619.393.522
D12.776.124.790.651.705.500.380
D12.776.377.715.548.114.619.393.522
D12.776.377.715.548.705.500.380
Unique ID
D007142
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007142
Annotation
gammopathy: coordinate IMMUNOGLOBULIN GAMMA-CHAINS (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA (IM) or HEAVY CHAIN DISEASE (IM), follow text; DF: IG GAMMA CHAIN
Scope Note
Heavy chains of IMMUNOGLOBULIN G having a molecular weight of approximately 51 kDa. They contain about 450 amino acid residues arranged in four domains and an oligosaccharide component covalently bound to the Fc fragment constant region. The gamma heavy chain subclasses (for example, gamma 1, gamma 2a, and gamma 2b) of the IMMUNOGLOBULIN G isotype subclasses (IgG1, IgG2A, and IgG2B) resemble each other more closely than the heavy chains of the other IMMUNOGLOBULIN ISOTYPES.
Entry Term(s)
Immunoglobulin gamma-Chain
Immunoglobulins, gamma-Chain
gamma Immunoglobulin Heavy Chain
gamma Immunoglobulin Heavy Chains
gamma-1-Immunoglobulin Heavy Chain
gamma-2a-Immunoglobulin Heavy Chain
gamma-2b-Immunoglobulin Heavy Chain
gamma-Chain Immunoglobulins
Pharm Action
Immunologic Factors
Registry Number
0
Previous Indexing
IgG (1973-1975)
Immunoglobulin Fragments (1973-1975)
Immunoglobulins, Heavy Chain (1975)
Public MeSH Note
2006; see IMMUNOGLOBULINS, GAMMA-CHAIN 1992-2005, see IMMUNOGLOBULINS, GAMMA CHAIN 1991, see IMMUNOGLOBULINS, HEAVY CHAIN 1976-1990
History Note
2006 (1976)
Date Established
1991/01/01
Date of Entry
1975/07/23
Revision Date
2005/07/15
Immunoglobulin gamma-Chains Preferred
gamma-2a-Immunoglobulin Heavy Chain Narrower
gamma-2b-Immunoglobulin Heavy Chain Narrower
gamma-1-Immunoglobulin Heavy Chain Narrower
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