MeSH Browser

MeSH Heading: Immunoglobulin gamma-Chains
Tree Number(s): D12.776.124.486.485.114.619.393.522; D12.776.124.486.485.705.500.380; D12.776.124.790.651.114.619.393.522; D12.776.124.790.651.705.500.380; D12.776.377.715.548.114.619.393.522; D12.776.377.715.548.705.500.380
Unique ID: D007142
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D007142
Annotation: gammopathy: coordinate IMMUNOGLOBULIN GAMMA-CHAINS (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA (IM) or HEAVY CHAIN DISEASE (IM), follow text; DF: IG GAMMA CHAIN
Scope Note: Heavy chains of IMMUNOGLOBULIN G having a molecular weight of approximately 51 kDa. They contain about 450 amino acid residues arranged in four domains and an oligosaccharide component covalently bound to the Fc fragment constant region. The gamma heavy chain subclasses (for example, gamma 1, gamma 2a, and gamma 2b) of the IMMUNOGLOBULIN G isotype subclasses (IgG1, IgG2A, and IgG2B) resemble each other more closely than the heavy chains of the other IMMUNOGLOBULIN ISOTYPES.
Entry Term(s): Immunoglobulin gamma-Chain; Immunoglobulins, gamma-Chain; gamma Immunoglobulin Heavy Chain; gamma Immunoglobulin Heavy Chains; gamma-1-Immunoglobulin Heavy Chain; gamma-2a-Immunoglobulin Heavy Chain; gamma-2b-Immunoglobulin Heavy Chain; gamma-Chain Immunoglobulins
Pharm Action: Immunologic Factors
Registry Number: 0
Previous Indexing: IgG (1973-1975); Immunoglobulin Fragments (1973-1975); Immunoglobulins, Heavy Chain (1975)
Public MeSH Note: 2006; see IMMUNOGLOBULINS, GAMMA-CHAIN 1992-2005, see IMMUNOGLOBULINS, GAMMA CHAIN 1991, see IMMUNOGLOBULINS, HEAVY CHAIN 1976-1990
History Note: 2006 (1976)
Date Established: 1991/01/01
Date of Entry: 1975/07/23
Revision Date: 2005/07/15

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Immunoproteins [D12.776.124.486]
      - Immunoglobulins [D12.776.124.486.485]
        
        Antibodies [D12.776.124.486.485.114]
        
        Immunoglobulin Isotypes [D12.776.124.486.485.114.619]
        
        Immunoglobulin G [D12.776.124.486.485.114.619.393]
        
        Alefacept [D12.776.124.486.485.114.619.393.131]
        
        Immunoglobulin gamma-Chains [D12.776.124.486.485.114.619.393.522]
        
        Immunoglobulin Gm Allotypes [D12.776.124.486.485.114.619.393.522.400]
        
        Immunoglobulins, Intravenous [D12.776.124.486.485.114.619.393.536]
        
        Long-Acting Thyroid Stimulator [D12.776.124.486.485.114.619.393.550]
        
        Muromonab-CD3 [D12.776.124.486.485.114.619.393.570]
        
        Rho(D) Immune Globulin [D12.776.124.486.485.114.619.393.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Immunoproteins [D12.776.124.486]
      - Immunoglobulins [D12.776.124.486.485]
        
        Immunoglobulin Subunits [D12.776.124.486.485.705]
        
        Immunoglobulin Heavy Chains [D12.776.124.486.485.705.500]
        
        Immunoglobulin alpha-Chains [D12.776.124.486.485.705.500.350]
        
        Immunoglobulin delta-Chains [D12.776.124.486.485.705.500.360]
        
        Immunoglobulin epsilon-Chains [D12.776.124.486.485.705.500.370]
        
        Immunoglobulin gamma-Chains [D12.776.124.486.485.705.500.380]
        
        Immunoglobulin Gm Allotypes [D12.776.124.486.485.705.500.380.500]
        
        Immunoglobulin mu-Chains [D12.776.124.486.485.705.500.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Serum Globulins [D12.776.124.790]
      - Immunoglobulins [D12.776.124.790.651]
        
        Antibodies [D12.776.124.790.651.114]
        
        Immunoglobulin Isotypes [D12.776.124.790.651.114.619]
        
        Immunoglobulin G [D12.776.124.790.651.114.619.393]
        
        Alefacept [D12.776.124.790.651.114.619.393.131]
        
        Immunoglobulin gamma-Chains [D12.776.124.790.651.114.619.393.522]
        
        Immunoglobulin Gm Allotypes [D12.776.124.790.651.114.619.393.522.400]
        
        Long-Acting Thyroid Stimulator [D12.776.124.790.651.114.619.393.550]
        
        Muromonab-CD3 [D12.776.124.790.651.114.619.393.570]
        
        Rho(D) Immune Globulin [D12.776.124.790.651.114.619.393.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Serum Globulins [D12.776.124.790]
      - Immunoglobulins [D12.776.124.790.651]
        
        Immunoglobulin Subunits [D12.776.124.790.651.705]
        
        Immunoglobulin Heavy Chains [D12.776.124.790.651.705.500]
        
        Immunoglobulin alpha-Chains [D12.776.124.790.651.705.500.350]
        
        Immunoglobulin delta-Chains [D12.776.124.790.651.705.500.360]
        
        Immunoglobulin epsilon-Chains [D12.776.124.790.651.705.500.370]
        
        Immunoglobulin gamma-Chains [D12.776.124.790.651.705.500.380]
        
        Immunoglobulin Gm Allotypes [D12.776.124.790.651.705.500.380.500]
        
        Immunoglobulin mu-Chains [D12.776.124.790.651.705.500.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Globulins [D12.776.377]
    - Serum Globulins [D12.776.377.715]
      - Immunoglobulins [D12.776.377.715.548]
        
        Antibodies [D12.776.377.715.548.114]
        
        Immunoglobulin Isotypes [D12.776.377.715.548.114.619]
        
        Immunoglobulin G [D12.776.377.715.548.114.619.393]
        
        Alefacept [D12.776.377.715.548.114.619.393.131]
        
        Immunoglobulin gamma-Chains [D12.776.377.715.548.114.619.393.522]
        
        Immunoglobulin Gm Allotypes [D12.776.377.715.548.114.619.393.522.400]
        
        Long-Acting Thyroid Stimulator [D12.776.377.715.548.114.619.393.550]
        
        Muromonab-CD3 [D12.776.377.715.548.114.619.393.570]
        
        Rho(D) Immune Globulin [D12.776.377.715.548.114.619.393.700]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Globulins [D12.776.377]
    - Serum Globulins [D12.776.377.715]
      - Immunoglobulins [D12.776.377.715.548]
        
        Immunoglobulin Subunits [D12.776.377.715.548.705]
        
        Immunoglobulin Heavy Chains [D12.776.377.715.548.705.500]
        
        Immunoglobulin alpha-Chains [D12.776.377.715.548.705.500.350]
        
        Immunoglobulin delta-Chains [D12.776.377.715.548.705.500.360]
        
        Immunoglobulin epsilon-Chains [D12.776.377.715.548.705.500.370]
        
        Immunoglobulin gamma-Chains [D12.776.377.715.548.705.500.380]
        
        Immunoglobulin Gm Allotypes [D12.776.377.715.548.705.500.380.500]
        
        Immunoglobulin mu-Chains [D12.776.377.715.548.705.500.500]

Immunoglobulin gamma-Chains Preferred

Concept UI: M0011131
Registry Number: 0
Scope Note: Heavy chains of IMMUNOGLOBULIN G having a molecular weight of approximately 51 kDa. They contain about 450 amino acid residues arranged in four domains and an oligosaccharide component covalently bound to the Fc fragment constant region. The gamma heavy chain subclasses (for example, gamma 1, gamma 2a, and gamma 2b) of the IMMUNOGLOBULIN G isotype subclasses (IgG1, IgG2A, and IgG2B) resemble each other more closely than the heavy chains of the other IMMUNOGLOBULIN ISOTYPES.
Terms: Immunoglobulin gamma-Chains Preferred Term
Term UI T633346
Date03/15/2005
LexicalTag NON
ThesaurusID NLM (2006); Immunoglobulins, gamma-Chain
Term UI T021393
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1976); gamma-Chain Immunoglobulins
Term UI T021392
Date01/01/1986
LexicalTag NON
ThesaurusID UNK (19XX); Immunoglobulin gamma-Chain
Term UI T633347
Date03/15/2005
LexicalTag NON
ThesaurusID NLM (2006); gamma Immunoglobulin Heavy Chain
Term UI T634015
Date03/22/2005
LexicalTag NON
ThesaurusID NLM (2006); gamma Immunoglobulin Heavy Chains
Term UI T634014
Date03/22/2005
LexicalTag NON
ThesaurusID NLM (2006)

gamma-2a-Immunoglobulin Heavy Chain Narrower

gamma-2b-Immunoglobulin Heavy Chain Narrower

gamma-1-Immunoglobulin Heavy Chain Narrower

Immunoglobulin gamma-Chains MeSH Descriptor Data 2024