MeSH Browser

MeSH Heading: Ketoconazole
Tree Number(s): D03.383.606.560
Unique ID: D007654
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D007654
Scope Note: Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.
Entry Term(s): Nizoral; R-41400; R41,400; R41400
Pharm Action: Antifungal Agents
14-alpha Demethylase Inhibitors
Cytochrome P-450 CYP3A Inhibitors
Registry Number: R9400W927I
Related Numbers: 65277-42-1
CAS Type 1 Name: Piperazine, 1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-, cis-
NLM Classification #: QV 252
Previous Indexing: Imidazoles (1966-1983); Piperazines (1966-1983)
Public MeSH Note: 84
History Note: 84
Date Established: 1984/01/01
Date of Entry: 1983/03/11
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Ketoconazole MeSH Descriptor Data 2024