MeSH Browser

MeSH Heading: Lipopolysaccharides
Tree Number(s): D09.400.500; D09.698.718.450; D10.494; D23.050.161.616.525; D23.946.123.329.500
Unique ID: D008070
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D008070
Annotation: oordinate with specific bacterium if pertinent
Scope Note: Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
Entry Version: LPS
Entry Term(s): Lipoglycans; Lipopolysaccharide
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2022/05/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0012577
Scope Note: Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)
Terms: Lipopolysaccharides Preferred Term
Term UI T024055
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1966); Lipopolysaccharide
Term UI T000996164
Date11/13/2019
LexicalTag NON
ThesaurusID NLM (2021); Lipoglycans
Term UI T024054
Date04/27/1981
LexicalTag NON
ThesaurusID UNK (19XX)

Lipopolysaccharides MeSH Descriptor Data 2024